... Patients with heart failure (HF) often suffered from concomitant insomnia. Non-benzodiazepine GABA receptor agonists (Z-drugs) are hypnotics commonly used for treating insomnia. The effect of Z-drugs on the outcomes of patients with HF is nonetheless sparse. Our study aims to investigate the association...

... information, helping clinicians more effectively treat their older patients. aged mirtazapine sleep initiation and maintenance disorders hypnotics and sedatives Quebec Research Network on Ageing Mirtazapine significantly reduces insomnia symptoms in older adults with chronic insomnia compared...

...*Tamayo Kobayashi; Fumitoshi Kodaka; Junpei Ishii; Keisuke Mori; Chihiro Saeki; Yoshiyuki Sakai; Masahiro Shigeta pregnancy database study anxiolytics and hypnotics antidepressant Abstract Background "The Guide for the Care of Pregnant Women with or Potentially With Psychiatric Disorders...

...*Jia-In Lee; Cheng-Fang Yen alcohol use sedatives/hypnotics LGB COVID-19 Abstract Background Increased alcohol and sedatives/hypnotics use are prevalent among lesbian, gay and bisexual (LGB) individuals, but very few prospective studies have examined the predictors of increased alcohol...

...://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Study Objectives This study assessed the utilization of potentially inappropriate medications (PIM) including oral sedative-hypnotic...

... of prescription hypnotic medications used (MEDS), assessed at 2, 4, 6, 9, and 12 months postrandomization. Results Mixed effects models revealed that, compared to ONLN, participants in STEP had greater reductions in ISI (p = .001; η² = 0.01) and MEDS (p = .019...

... ^{‑ 4} Psychoactive drugs are a particular concern because they can cause psychomotor impairment that may increase the risk of MVCs. Nonbenzodiazepine hypnotic drugs (“Z-drugs”), including zolpidem, eszopiclone, and zaleplon, for the treatment of insomnia are one of the most commonly used psychoactive...

... Biomedical Laboratory Research and Development Service Career Development BX004905 automated sleep–wake scoring deep learning transfer learning translational sleep research basic sleep research in vivo pharmacology hypnotics Alzheimer’s disease model Abstract Sleep–wake scoring is a time-consuming...

... into clinical care. He not only contributed early to the pharmacology of sleep and the effects of hypnotics, but he was also a pioneer in “sleep epidemiology.” His “Prevalence of sleep disorders in the Los Angeles metropolitan area” study of 1979 was the first rigorous epidemiological study on sleep...

... The psychotropic medication group included patients with RA prescribed psychotropic medications [hypnotics/sedatives, antidepressants, antipsychotics, and anxiolytic (benzodiazepines) drugs]. Poisson regression with robust variance was performed to investigate the relationship between falls and the use...

... included antimuscarinic toxicity (n = 19), polysubstance toxicity (n = 16), sedative withdrawal (n = 10), unknown agitation (n = 7), sympathomimetic toxicity (n = 5), baclofen withdrawal (n = 3), unknown ingestion (n = 3), sedative-hypnotic toxicity (n = 2), antipsychotic toxicity (n = 2), hallucinogenic...

... benzodiazepines cohort studies general practice hypnotics and sedatives inappropriate prescriptions departmental resources Key messages - Twenty-two percent of GP consultations by older adults resulted in a prescription of benzodiazepine or a Z-drug. - No GP characteristics were associated with BZD/ZD...

... and hypnotic use, and whether the prevalence depended on patient characteristics such as sex, age, education, having children living at home, sleep duration, and circadian preference (morningness–eveningness). In Norway, GPs have since 2001 been organized in a patient list system in which each citizen has...

.../licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract In reviewing my studies, some of which are nearing the half century mark, I’ve described work on sleep-related growth hormone, the effects of hypnotics...

...) combined with supervised open-label tapering is effective for helping hypnotic-dependent patients discontinue their hypnotics. This study tested whether slowing the tapering pace and blinding the tapering process enhance outcomes. Methods Seventy-eight benzodiazepines (BZD) or benzodiazepine receptor...

...). The longer patients use CPAP, the greater the benefit. Nonetheless, adherence to CPAP is less than ideal. The improvement of CPAP adherence with non-benzodiazepine sedative hypnotics (NBSH) is controversial. Our review and meta-analysis demonstrated that NBSHs especially eszopiclone, may improve CPAP...

... and/or sedative-hypnotic medication administration at the time of assessment. CASPER includes nursing home characteristics such as ownership, number of beds, and proportion of Medicaid residents. We also used acuity-adjusted nurse staffing data from the CMS Nursing Home Compare database to adjust for the patient...

... troponin I (>0.04 pg/mL, P = .02), leukocytosis (>10 × 10⁹/L, P < .001), and neutrophilia (>75 × 10⁹/L, P < .001) predicted unfavorable clinical outcomes. In contrast, the administration of hypnotics was significantly associated with favorable...

... but is permissive for those systems to be recruited in the setting of a task demand. Concerns regarding neurocognitive effects of hypnotic medications during unanticipated awakenings during sleep have led to a Food and Drug Administration (FDA) warning for all hypnotic drugs. These concerns are particularly...

... mechanically ventilated patients admitted to our CICU from March 1, 2011, to April 13, 2013. On March 1, 2012, an analgosedation protocol was implemented. Patients in the pre-implementation group were managed at the cardiologist’s discretion, which consisted of a continuous sedative-hypnotic approach...