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Keywords: hypercalcemia
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Journal Article
Mostafa Salama and others
JCEM Case Reports, Volume 3, Issue 5, May 2025, luaf066, https://doi.org/10.1210/jcemcr/luaf066
Published: 15 April 2025
...Mostafa Salama; Alaa Al Nofal; Peter Tebben A variety of treatment approaches can be utilized for management of hypercalcemia in HPP. This includes intravenous fluids, calcitonin, and loop diuretics for short-term management. Longer-term glucocorticoid therapy and low dietary calcium intake have...
Journal Article
Christine K Persaud and others
JCEM Case Reports, Volume 3, Issue 5, May 2025, luaf060, https://doi.org/10.1210/jcemcr/luaf060
Published: 28 March 2025
... . 10 10 2024 06 03 2025 28 03 2025 Published by Oxford University Press on behalf of the Endocrine Society 2025. 2025 This work is written by (a) US Government employee(s) and is in the public domain in the US. See the journal About page for additional terms. Abstract Hypercalcemia...
Journal Article
Bramara N Godasi and David S Schade
JCEM Case Reports, Volume 3, Issue 4, April 2025, luaf050, https://doi.org/10.1210/jcemcr/luaf050
Published: 19 March 2025
...Bramara N Godasi; David S Schade The biological half-life of calcitriol is 4 to 6 hours, thereby making it difficult to identify surreptitious calcitriol ingestion after treating the hypercalcemia acutely with rehydration. However, the calcemic response can persist for more than 24 hours after...
Journal Article
Oyunbileg Magvanjav and Clemens Bergwitz
JCEM Case Reports, Volume 3, Issue 4, April 2025, luaf031, https://doi.org/10.1210/jcemcr/luaf031
Published: 19 March 2025
... by 60 mg every 6 months. We present a rare case of a patient with GCTB-PDB with hypercalcemia from elevated 1,25(OH)2D. Hypercalcemia occurring in GCTB and/or PDB is atypical. After reviewing the English biomedical literature in PubMed using the search terms hypercalcemia, giant...
Journal Article
An Song and others
The Journal of Clinical Endocrinology & Metabolism, dgaf107, https://doi.org/10.1210/clinem/dgaf107
Published: 03 March 2025
... for treating hypercalcemia of malignancy, but data on its efficacy for hypercalcemia related to primary hyperparathyroidism (PHPT) are limited. Objective To compare the efficacy and safety of denosumab with zoledronic acid in PHPT-related hypercalcemia. Methods We retrospectively collected data from 29...
Journal Article
Gonçalo Tardão and others
Journal of Surgical Case Reports, Volume 2025, Issue 2, February 2025, rjaf046, https://doi.org/10.1093/jscr/rjaf046
Published: 21 February 2025
... with systemic conditions. PTK is an effective and safe procedure for managing CBK, and can provide complete visual rehabilitation. calcific band keratopathy cornea hypercalcemia photherapeutic keratectomy Calcific band keratopathy (CBK) is a corneal degeneration characterized by the accumulation of fine...
Journal Article
Jeremy A Knott and others
JCEM Case Reports, Volume 3, Issue 2, February 2025, luaf011, https://doi.org/10.1210/jcemcr/luaf011
Published: 04 February 2025
..., distribution, and reproduction in any medium, provided the original work is properly cited. See the journal About page for additional terms. Abstract Hypercalcemia is frequently encountered in clinical practice; however, sarcoidosis-induced hypercalcemia is relatively uncommon and requires careful evaluation...
Journal Article
Aravind L and others
JCEM Case Reports, Volume 3, Issue 1, January 2025, luae233, https://doi.org/10.1210/jcemcr/luae233
Published: 17 January 2025
...Aravind L; Arun Viswanath S; Ninoo George G; Ranjit Jeyasekharan; Deepak David; Jerin J Ovett Although vitamin D intoxication is a common cause of hypercalcemia in our setting, we were unable to definitively document vitamin D abuse in our patient. It was only presumed based on 25(OH)D levels...
Journal Article
Kazuhiko Kato and others
JBMR Plus, Volume 9, Issue 3, March 2025, ziae178, https://doi.org/10.1093/jbmrpl/ziae178
Published: 15 January 2025
... the original work is properly cited. Abstract The challenge of managing acute hypercalcemia in patients diagnosed with hypercalcemia of malignancy (HCM) merits further attention. Elevated levels of PTHrP may be a risk factor for treatment resistance in acute hypercalcemia; however, few studies have tested...
Journal Article
Jorge Fuentes-Sánchez and others
Journal of Surgical Case Reports, Volume 2025, Issue 1, January 2025, rjae022, https://doi.org/10.1093/jscr/rjae022
Published: 07 January 2025
... in longitudinal axis. (B) Axial CT: lytic lesion with cortical destruction at trochanteric level. Due to the intense pain, he was admitted to hospital. During admission he presented hypercalcemia (maximum corrected calcium level, 14.5 mg/dL). After evaluation by the internal medicine service, malignant...
Journal Article
Anand D Gandhi and others
JCEM Case Reports, Volume 2, Issue 12, December 2024, luae217, https://doi.org/10.1210/jcemcr/luae217
Published: 28 November 2024
..., and reproduction in any medium, provided the original work is properly cited. See the journal About page for additional terms. Abstract Hypercalcemia may be induced by a variety of etiologies, most commonly primary hyperparathyroidism. Although primary hyperparathyroidism represents a relatively common...
Journal Article
Lutfor Nessa and others
JCEM Case Reports, Volume 2, Issue 12, December 2024, luae203, https://doi.org/10.1210/jcemcr/luae203
Published: 14 November 2024
... 14 11 2024 Hypercalcemia can signal malignancy, necessitating thorough evaluation even when primary hyperparathyroidism is suspected. Diagnostic complexity underscores the need for considering various etiologies in hypercalcemia cases. Multidisciplinary collaboration optimizes management...
Journal Article
Katherine I Wolf and others
JCEM Case Reports, Volume 2, Issue 12, December 2024, luae209, https://doi.org/10.1210/jcemcr/luae209
Published: 14 November 2024
... liver masses measuring upwards of 6.1 × 5.4 × 6.5 cm in the right inferior pole, suggesting neoplasm. Biochemical evaluation demonstrated leukocytosis, anemia, and hypercalcemia to 12.3 mg/dL (3.07 mmol/L) (reference range [RR] 8.2-10.2 mg/dL; 2.2—2.6 mmol/L) without other electrolyte abnormalities...
Journal Article
Na Hyun Kim and others
JCEM Case Reports, Volume 2, Issue 12, December 2024, luae208, https://doi.org/10.1210/jcemcr/luae208
Published: 07 November 2024
... parathyroid carcinoma. parathyroid carcinoma multimodal treatment hypercalcemia Parathyroid carcinoma is an extremely rare endocrine malignancy, comprising only 0.005% of all cancers [ 1 , 2 ]. The primary treatment for parathyroid carcinoma is surgery; however, 50% of the patients develop local...
Journal Article
Nipith Charoenngam and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 2, February 2025, Pages 297–302, https://doi.org/10.1210/clinem/dgae769
Published: 01 November 2024
.../pages/standard-publication-reuse-rights ) Abstract Context Genetic testing of the calcium-sensing receptor (CASR) gene is crucial for confirming diagnoses of familial hypocalciuric hypercalcemia type I (FHH1) and autosomal dominant hypocalcemia type I (ADH1). Therefore, we created a publicly...
Journal Article
Carly Barron and others
JCEM Case Reports, Volume 2, Issue 11, November 2024, luae190, https://doi.org/10.1210/jcemcr/luae190
Published: 23 October 2024
...-month-old, full-term female developed growth failure, feeding intolerance, and irritability starting at 10 months of age. She was found to have a serum calcium level of 3.75 mmol/L (15 mg/dL) (reference range, 2.13-2.62 mmol/L; 8.5-10.5 mg/dL), consistent with severe hypercalcemia. She had bilateral...
Journal Article
Lakshmipriya Thandiyekkal Rajan and others
JCEM Case Reports, Volume 2, Issue 11, November 2024, luae198, https://doi.org/10.1210/jcemcr/luae198
Published: 22 October 2024
...://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. See the journal About page for additional terms. Abstract Hypercalcemia is a relatively common clinical problem, and evaluation for its etiology may...
Journal Article
Wei Du and others
The Journal of Clinical Endocrinology & Metabolism, dgae735, https://doi.org/10.1210/clinem/dgae735
Published: 16 October 2024
... heterozygous CASR variants from individuals with familial hypocalciuric hypercalcemia 1 (FHH1: Y63C, I81T, Q459R, W818stop) or autosomal dominant hypocalcemia 1 (ADH1: R955stop). Methods Total and cell surface expression levels of wild-type (WT) and variant CaSRs expressed in human embryonic...
Journal Article
Dianna Luong and others
JCEM Case Reports, Volume 2, Issue 9, September 2024, luae159, https://doi.org/10.1210/jcemcr/luae159
Published: 05 September 2024
... a pregnant individual who returned unexpectedly low PTH levels. We describe a 27-year-old female patient who presented at 25 weeks gestation with pancreatitis and hypercalcemia. Primary hyperparathyroidism was suspected but variable PTH results led to uncertainty and an assay error was considered. PTH...
Journal Article
Sam Kafai Yahyavi and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 649–657, https://doi.org/10.1210/clinem/dgae606
Published: 03 September 2024
... of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Context Cosmetic paraffin oil injections can lead to granuloma formation, causing hypercalcemia and kidney failure. Objective This study explores whether...