... functioning in people living with neurodegenerative diseases and may be a valuable tool for identifying specific socioemotional impairments in the context of neurodegenerative disease. Alzheimer’s disease Caregivers Frontotemporal dementia Informant-reports Measurement development National Institutes...

... Ferrari; Carlo Caltagirone; Alessandro Martorana; Giacomo Koch Correspondence to: Giacomo Koch Department of Clinical and Behavioural NeurologySanta Lucia Foundation IRCCSVia Ardeatina 306, Rome 00173, Italy E-mail: [email protected] Graphical Abstract Graphical Abstract frontotemporal dementia...

... changes are a central feature of frontotemporal dementia (FTD); they occur in both behavioural-variant (bvFTD) and semantic dementia (SD)/semantic-variant primary progressive aphasia subtypes. In this study, we addressed two current clinical knowledge gaps; (i) are there qualitative or clear distinctions...

... information please contact [email protected]. Abstract Background Frontotemporal dementia (FTD) is a group of neurodegenerative disorders with diverse clinical and neuropathological features. In vivo neuropathological assessments of FTD at an individual level have not hitherto been successful...

[email protected] 16 08 2024 06 01 2025 07 02 2025 21 02 2025 Metz et al. report that machine learning can effectively differentiate frontotemporal dementia subtypes, combining...

... of these factors for humans is unclear. We examined five previously identified brain rejuvenation factors in cerebrospinal fluid of adults with autosomal dominant forms of frontotemporal dementia and sporadic Alzheimer’s disease. Our frontotemporal dementia cohort included 100 observationally followed adults...

... largely unclear. In behavioural variant frontotemporal dementia, social cognitive abilities are profoundly impaired, whereas these are typically spared in Alzheimer’s disease. If musicality indeed shares a neuroanatomical basis with social cognition, it could be hypothesized that clinical...

... frontotemporal dementia; CDR = clinical dementia rating; CDR plus NACC FTLD = Clinical Dementia Rating Dementia Staging Instrument plus National Alzheimer's Coordinating Center Behavior and Language Domains; CDR-sb = clinical dementia rating sum of boxes; MMSE = mini-mental state examination; nfvPPA = non-fluent...

... invasive imaging tool can be used to identify dementia after more researches to find disease specific changes. Magnetic Resonance Spectroscopy Alzheimer’s Frontotemporal dementia Dementia of Lewy body ii398 | QJM: An International Journal of Medicine, 2024, Vol. 117, Suppl. 2 accurate detection of tumor...

... an abstract non-social synonym judgement task with items matched to the social concepts for lexical frequency, imageability and semantic diversity. ^{32 , 72} behavioural variant frontotemporal dementia semantic dementia social concept temporal lobe epilepsy trans-diagnostic Medical Research...

... degeneration spectrum. This 20-min test can be administered à la carte and offers an alternative to detailed comprehensive neuropsychological evaluations. Test construction Assessment Alzheimer’s disease Frontotemporal dementia Norms/normative studies Cognitive screening La Chaire de Recherche...

... Alzheimer’s disease (AD). However, limited data exist for rarer types of neurodegenerative diseases, such as behavioral variant frontotemporal dementia (bvFTD). This study aims to analyze EEG power spectra and sleep stage transitions in bvFTD patients, hypothesizing that bvFTD may show distinctive sleep stage...

...Jack Rivers-Auty; Christopher Hoyle; Ayesha Pointer; Catherine Lawrence; Stuart Pickering-Brown; David Brough; Sarah Ryan Graphical Abstract Graphical Abstract c9orf72 frontotemporal dementia ALS NLRP3 inflammasome Alzheimer's Society 10.13039/501100000320 484 (AS-JF-18b-014...

... variant frontotemporal dementia, bvFTD). ⁸ Typically, variants are diagnosed as independent entities based on discrete symptoms and corresponding neural-biological dysfunction profiles. In the reality of everyday clinics, there are many exceptions to such ‘textbook’ cases. Patients frequently...

... [email protected] Abstract Metabolic changes are observed in patients with both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Although regulation of metabolic processes in the CNS is predominantly carried out within the hypothalamus, extra-hypothalamic CNS areas contain metabolic...

.../licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Frontotemporal dementia is marked by changes in behaviour, language and executive control, in association with multiple neuropathological substrates...

... through our RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract Pathogenic variants in the UBQLN2 gene cause X-linked dominant amyotrophic lateral sclerosis and/or frontotemporal dementia...

... 18 04 2024 09 05 2024 For the first time in behavioural variant frontotemporal dementia (bvFTD), Devenney et al. characterized the neural and cognitive profile associated with hallucination vulnerability. The authors report dysfunctions specific to attentional and visual subsystems...

... occurs in multiple dementia syndromes, including behavioural variant frontotemporal dementia, and dementia of the Alzheimer’s type. Morphometric similarity networks are a relatively new method for examining brain structure and can be used to calculate measures of network integrity on large scale brain...

...Emma L Clayton; Laura Huggon; Michael A Cousin; Sarah Mizielinska Abstract Frontotemporal dementia and amyotrophic lateral sclerosis are common forms of neurodegenerative disease that share overlapping genetics and pathologies. Crucially, no significantly disease-modifying treatments are available...