...Oxford University Press Temporal lobe epilepsy, as discussed in this chapter, is a focal epilepsy that involves primarily the limbic structures of the medial temporal lobe (amygdala, hippocampus, and entorhinal cortex). In recent years animal models have been developed that mirror the pathology...

...Oxford University Press Select epilepsy syndromes can begin in childhood but are also seen in adulthood. Among these are the family of absence epilepsies, generalized tonic-clonic seizures, Lennox-Gastaut syndrome, and a host of focal epilepsy syndromes. This chapter discusses the clinical features...

.... genetics somatic mosaicism focal epilepsies focal cortical dysplasia mTOR pathway malformations of cortical development MCDs focal cortical dysplasia FCD focal cortical dysplasia type II FCDII mTOR mechanistic target of rapamycin mTORC1 mTOR complex 1 somatic mutations DEPDC5 mild malformations...