... Factor V Leiden (FVL), Prothrombin G20210A and Methyl Tetra Hydro Folate Reductase (MTHFR) C677T Mutations should be routinely performed in patients with Budd–Chiari syndrome (BCS). However, the prevalence of these mutations in such patients is substantially variable. This is the first study in clinical...

... with the G1691A mutation of the factor V Leiden (FVL) gene ( Sergi et al., 2015 ), whereas in the meta-analysis performed by Gao et al., only the association between the G20210A mutation of the prothrombin gene (PGM) and RPL was evaluated ( Gao and Tao, 2015 ). Furthermore...

... Factor V Factor X Factor V Leiden Coagulation factor assays are commonly ordered laboratory tests used for the assessment of prolonged screening assays, such as prothrombin time (PT) and activated partial thromboplastin time (aPTT), and the clinical workup of patients with bleeding disorders...

... and the Danish Environmental Protection Agency. TRIAL REGISTRATION NUMBER Not applicable. factor V Leiden prothrombin G20210A mutation thrombophilia male fertility sperm count spermatogenesis evolution Factor V Leiden (FVL) is a gain-of-function single point mutation (Arg506Gln) in the gene coding...

... costs. Factor V Leiden Activated protein C resistance Cost-effectiveness Cost-benefit analysis Thrombophilia Venous thromboembolism (VTE) is a multifactorial disease with a global incidence of 0.75 to 2.69 cases per 1,000 people per year. ¹ Acquired risk factors for VTE are common...

... that might potentially be used to stratify pregnancies according to risk of complications. complications epidemiology F5 gene factor V Leiden genetics meta-analysis severe preeclampsia systematic review thrombophilia Editor's note: This article also appears on the Web site...

... regression analyses revealed that, of the potential prognostic factors, only the factor V Leiden mutation was significantly associated with a shorter time to conception (Table  II ). After backward elimination, only factor V Leiden mutation emerged as a significant predictor of a shorter time to conception...

... showed MTHFR A1298C/MTHFR C677T/prothrombin G22010A mutations. The mean age of these 3 patients, all of whom were male, was 38.7 (5.13) years. Abstract Objectives To investigate the frequency and type of Factor V Leiden (FVL), prothrombin, and methylenetetrahydrofolate reductase (MTHFR) mutations...

... the performance of a Russell viper venom–based activated protein C resistance (APCR) screening test relative to DNA analysis for the factor V Leiden mutation. Methods: We evaluated the concordance between Pefakit APCR screening results and DNA analysis for 435 patients homozygous (n = 11), heterozygous (n...

.... The objectives of this study were: (i) to compare the prevalence of Factor V Leiden (FVL) and prothrombin gene G20210A mutation (PGM) in women undergoing IVF to women with spontaneous pregnancy; (ii) to compare the IVF outcomes and the risk of complications in FVL and PGM carrier to non-carrier women. METHODS...

...Wan Zaidah Abdullah; Subashini Kumaraguru; Selamah Ghazali; Narazah Mohd Yusoff Corresponding Author: Wan Zaidah Abdullah, MD, [email protected] 05 12 2009 29 12 2009 31 12 2009 © American Society of Clinical Pathologists 2010 Abstract Background: Factor V Leiden (FVL) (G1691A...

... abnormalities were noted and results of a transvaginal ultrasound and hysterosalpingogram were normal. Table 1 . 21 09 2009 19 10 2009 © American Society of Clinical Pathologists 2010 recurrent pregnancy loss thrombophilia infertility Factor V Leiden mutation activated protein C resistance...

...Sanjay Chaubey; Simon J. Davidson; Anthony C. DeSouza A review by Lee et al. from Canada reported results in 165 patients diagnosed as HIT over a 14-year period and found no associated risk between factor V Leiden and severity of HIT. However, in this study no distinction was made between patients...

.... For commercial re-use, please contact [email protected] Factor V Leiden sunitinib thrombotic microangiopathy VEGF inhibitors Haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are closely related disorders characterised by non-immune microangiopathic haemolytic anaemia...

... Pathologists 2008 Abstract Thrombotic disease is a significant cause of mortality and morbidity, with an estimated lifetime risk of greater than 10% in Western populations. One of the most common hereditary thrombophilias is the factor V Leiden mutation, which is identified with a screening assay...

..., AL 35249-7331. © American Society of Clinical Pathologists 2008 Abstract Testing for factor V Leiden can be performed with a molecular assay or a test for activated protein C resistance. We noted that physicians in our institution tended to order the molecular test 80% of the time...

... Medical Center, 330 Brookline Ave, Boston, MA 02215. Supported by Abbott Laboratories † Deceased. © American Society of Clinical Pathologists 2007 Abstract Factor V Leiden (FVL) and prothrombin (PT) G20210A mutations are associated with increased risk of deep venous thrombosis, pulmonary embolism...

... polymorphisms do not differ in patients with IBD-VC and TC. FV R506Q and PAI-1 gene polymorphisms might be associated with the increased risk of development of vascular complications in IBD. genetics Crohn's disease factor V Leiden PAI-1 thrombosis ulcerative colitis Inflammatory bowel...

... into account. DVT, deep venous thrombosis FVL, factor V Leiden HRT, hormone replacement therapy OCP, oral contraceptive pill VTE, venous thromboembolism venous thrombosis thrombosis thromboembolism pulmonary embolism thrombophilia Thrombophilia is a disorder of haemostasis in which there is a tendency...

...Yakup Ekmekci; Kenan Keven; Nejat Akar; Yonca Egin; Sule Sengul; Sim Kutlay; Sehsuvar Erturk; Bulent Erbay avascular necrosis factor V Leiden kidney transplantation prothrombin G20210A thrombophilia Avascular necrosis (AVN) of the femoral head is a rare, debilitating complication seen after...