... localized to a specialized region of the endoplasmic reticulum (ER), called the ER exit site (ERES), through its interaction with Sec31A. Sec31A is an outer coat protein of coat protein complex II (COPII) and is recruited from the cytosol to the ERES to form COPII-coated transport vesicles. I will overview...

...Daniele Camboni; Matthaeus Zerdzitzki; Stephan Hirt; René Tandler; Michael Weyand; Christof Schmid The purpose of this study was to compare the incidence of DL exit site infection using two different DL materials at percutaneous skin. Although the redesigned DL facilitates the placement of silicone...

..., Hammersmith Hospital, London. All the patients had used prophylactic topical mupirocin at their exit sites, which were clinically monitored for signs of infection at their regular clinic visits (every 6–8 weeks). ESIs were defined by the presence of pericatheter erythema, tenderness and purulent drainage...

... ]. Nevertheless, home visits may highlight when retraining is necessary, with one study finding that 23% of the centre's patients were not following exchange protocol procedures and 11% were non-compliant with the exit-site protocol procedures [ 29 ]. A number of randomized trials have examined whether...

... and a silicone suture wing taken from a central venous catheter (CVC) set (7 or 8.5 French, but the second is better), routinely used for fixing the catheter at the skin. The StatLock device was placed on the skin ∼4–7 cm from the exit site (also depending on the need and comfort of the patient) (Fig. 1...

... to: Manish M. Sood; E-mail: [email protected] 19 7 2012 21 11 2012 21 12 2012 © The Author 2013. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved 2013 Abstract Background Exit site infections (ESIs) have been previously associated with the development...

..., mupirocin applied to the exit site will not prevent infections that are due to touch contamination (common skin organisms, such as coagulase-negative Staphylococcus ). Prevention of peritonitis due to contamination most likely lies in attention to training, reinforcement of training and use of up...

... ’, ‘peritonitis’ and ‘exit-site infection’. The search was restricted to English-language trials published up to March 2009. The following criteria were used in selecting studies for inclusion: (1) the research population consisted of adults (age ≥ 18 years) undergoing PD; (2) the study was a randomized...

... demonstrated practices Kidney Int Suppl 2006 103 S44 S54 17 Wadhwa NK Reddy GH Exit-site care in peritoneal dialysis Contrib Nephrol 2007 154 117 124 18 De Vecchi A Corciulo R Salomone M Catheter-related interventions to prevent peritonitis in peritoneal...

...Rapur Ram; Guditi Swarnalatha; Neela Prasad; Kaligotla Venkata Dakshinamurty Fig. 1. Full thickness necrosis of anterior abdominal wall. Fig. 2. Another view of exposed rectus muscle. There are very few reports [ 1–4 ] of peritonitis and exit site infection due to zygomycosis. In all...

... and exit-site infections (ESI) are major causes of morbidity in peritoneal dialysis (PD) patients. The application of topical mupirocin to exit sites reduces such complications, and prolongs life in PD. Since the year 2000, this topical treatment has been used in our hospital on new PD patients. We...

...Christopher Thiam-Seong Lim; Kok-Seng Wong; Marjorie Wai-Yin Foo Fig. 1. Impact of mupirocin on PD exit-site infections. SA, Staphylococcus aureus; MRSA, methicillin-resistant Staphylococcus aureus; Strep. Sp, Streptococcus species. Fig. 2. Impact of mupirocin on PD...

...Thierry Lobbedez; Michael Gardam; Helen Dedier; Dorothy Burdzy; Maggie Chu; Sharon Izatt; Joanne M. Bargman; Sarbjit V. Jassal; Stephen Vas; James Brunton; Dimitrios G. Oreopoulos catheter exit site mupirocin resistance Staphylococcus aureus peritoneal dialysis Staphylococcus...

... an increased risk of peritonitis and exit‐site infection for peritoneal dialysis (PD) patients. The aim of the present study was to examine the incidence of colonization by other peritoneal pathogens, and more specifically by Gram‐negative bacteria (GNB), among PD patients, and to disclose its potential...

... automated PD). Median time from heart or heart–lung transplantation to ESRD was 9 years (range 1–13 years), and median age at introduction of renal replacement therapy was 51 years (range 23–66 years). The frequency of exit‐site infections, peritonitis, and PD survival (including technique failure and death...

... complications, and the time intervals to first PD‐related infection were compared. Results.  Clinical characteristics, incidence of exit‐site infection (ESI), and time intervals to first ESI were similar in the TB and APD groups. The incidence of peritonitis in the APD group (1.22 episodes/100 patient‐months...

..., especially those caused by Mycobacterium fortuitum and Mycobacterium chelonae, are becoming highly prevalent [ 1 ]. Several cases of peritonitis due to these organisms among patients receiving peritoneal dialysis (PD) have been described [ 2 , 3 ]. Although peritoneal catheter exit‐site...

... Dialysis and Transplant Association 2000 Abstract Background. Partial replantation (i.e. replacement of the extraperitoneal portion of the catheter with creation of a new subcutaneous tunnel) has been suggested to avoid catheter removal in patients with persistent exit-site/tunnel infection (ESTI...

... a survey of the current practice in the ment of exit site infections, and bacteraemia. UK of long term haemodialysis catheters, long term Results. (1) Total number of questionnaires returned being defined as expected use life of the catheter for 66 (81.5 (2) 63.6% of renal units used double lumen more...

... Transplantation Frequent involvement of the internal cuff segment in CAPD peritonitis and exit-site infection—an ultrasound study Z. Korzets1, A. Erdberg1, E. Golan1, S. Ben-Chitrit1, M. Verner2, V. Rathaus2 and J. Bernheim1 Departments of 'Nephrology, and 2Radiology, Meir General Hospital, Kfar Saba...