... reporting of influenza laboratory results and vaccine doses administered in the state of California can provide estimates of seasonal influenza vaccine effectiveness (VE). We analyzed linked influenza immunization registry and laboratory reporting data among California residents aged ≥6 months tested...

..., and reproduction in any medium, provided the original work is properly cited. Abstract Assessing the time-varying effectiveness of coronavirus disease 2019 (COVID-19) vaccines is critical to guiding vaccine strategies and public health policies. We developed a Bayesian framework to estimate the waning vaccine...

... mean matching, assuming that data were missing at random. Baseline characteristics, randomization, and clinical effect at day 90 were included in the imputation model as explanatory variables to select the 5 most comparable patients without missing data. All analyses were conducted on an intention...

... Background Dolutegravir (DTG) is a preferred anchor antiretroviral therapy (ART) for children and adolescents living with HIV (CALHIV). Methods We assessed the effectiveness and safety of DTG in CALHIV aged 0-18 years at DTG start in routine care in Europe and Thailand, including viral suppression...

... for favorable outcomes. Despite initiatives like Acute Stroke Care Maps (ASCaMs) in China aiming to improve care continuity and thrombolysis rates, the long-term effectiveness of these interventions in urban settings remains underexplored. Methods This retrospective cohort study investigates the role...

.... Vaccine effectiveness (VE) against influenza–associated hospitalization was calculated as (1 − adjusted odds ratio for vaccination) × 100%. Results Among 7690 patients, including 1170 influenza cases (33% vaccinated) and 6520 controls, VE was 40% (95% CI: 31%–48%) with varying estimates by age (18–49...

... Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. delta hepatitis HDV screening viral hepatitis cost-effectiveness Centers for Disease Control...

... from patients and other critical stakeholders. The Institute for Clinical and Economic Review (ICER) brings drug pricing and coverage decisions into the open by conducting independent assessments of effectiveness and value that undergo a public process. While many stakeholders are invited...

...Manuela Deidda; Helen Minnis; Karen Crawford; Robin Young; Gary Kainth; Julia Donaldson; Matt Forde; Alex McConnachie; Christopher Gillberg; Marion Henderson; Philip Wilson; Kathleen A Boyd; Emma McIntosh children cost effectiveness mental health NIHR Public Health Research Programme 10.13039...

... Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Abstract Observational studies evaluating the effectiveness of cancer screening are often biased due to non-alignment at time zero, which can be avoided by target trial emulation (TTE...

... Bictegravir combined with emtricitabine and tenofovir alafenamide (BIC/FTC/TAF) has shown high effectiveness and a good tolerability profile [ 5–7 ], comparable to dolutegravir (DTG)–based regimens up to 144 weeks of follow-up [ 8 , 9 ]. As a result, BIC/FTC/TAF and DTG-based therapies are now preferred...

... page on our site—for further information please contact [email protected]. Cost-effectiveness ratios were determined by calculating the difference in the total costs divided by the difference in quality-adjusted life-years (QALYs) gained through prevention of deaths averted over the 90-day...

... identified three clinically relevant screening thresholds: an receiver operating characteristic (ROC)-optimal cutoff at 0.45 million sperm/ml, a high-sensitivity cutoff at 8 million sperm/ml, and a cost-effective threshold at 1 million sperm/ml. WHAT IS KNOWN ALREADY YCMs are the second most common...

...-rights ) Abstract Whether perceived message effectiveness (PME) can be diagnostic for the differences of actual message effect (AME) in campaign message pretesting and how the diagnosticity of PME should be tested have been controversial. To address these issues, we conducted a survey involving 19...

... between each risk factor and clinical outcome was derived from Mendelian randomization studies. Mendelian randomization quantifies the effect of each risk factor over the lifetime; for LDL-C, we applied these estimates by assuming that age- and sex-specific CVD risk was proportional to the weighted mean...

... and observational studies is critical to inform clinical decision making. We conducted a systematic literature review with meta-analysis to summarize the effectiveness of remdesivir among hospitalized adults. Methods We systematically searched MEDLINE, Embase and Cochrane Library databases for interventional...

... cost-effectiveness analysis community care EQUAL Research Programme Consortium Somalia, in particular, is at the forefront of these concerns, with continued health and humanitarian crises caused by and resulting in conflict, instability, and poverty, along with uncertainty from the growing threat...

... Network (SARInet plus) respiratory virus surveillance pandemic preparedness genomic surveillance influenza vaccine effectiveness Acute respiratory infections are a leading cause of illness and death worldwide [ 1 ]. Because of the health and economic impact, the prevention of and preparedness...

...-averted influenza illnesses among young children and older adults in Chile, Guyana, and Paraguay. Methods We gathered country- and target population-specific data on monthly influenza hospitalizations, vaccine coverage, and vaccine effectiveness from surveillance records and immunization registries...

... through our RightsLink service via the Permissions link on the article page on our site–for further information please contact [email protected]. ABSTRACT Objective To evaluate tofacitinib real-world safety/effectiveness in patients with rheumatoid arthritis (RA) in Japan in a 3-year all...