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Journal Article
Does MDMA have treatment potential in sexual dysfunction? A systematic review of outcomes across the female and male sexual response cycles
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Ava Wexler and others
Sexual Medicine Reviews, Volume 12, Issue 1, January 2024, Pages 26–34, https://doi.org/10.1093/sxmrev/qead046
Published: 26 October 2023
... and Meta-Analyses) guidelines. Search terms utilized were “MDMA” or “ecstasy” in combination with “desire,” “arousal,” “lubrication,” “orgasm,” “pleasure,” “libido,” “erection,” and “ejaculation.” Inclusion criteria for this review were MDMA use by study subjects and sexual outcomes in at least 1 domain...
Journal Article
Transcending the body: music, chastity and ecstasy in Reni’s St Cecilia playing the violin
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Sigrid Harris
in
Early Music
Early Music, Volume 51, Issue 1, February 2023, Pages 91–108, https://doi.org/10.1093/em/caac067
Published: 03 January 2023
... in hand, in a state of musical ecstasy. Highlighting the importance of this painting, which thus far has received little attention from musicologists, this article seeks to unpack the ambiguities inherent in Reni’s portrayal of the virgin martyr as a violinist. Taking the complex tradition linking Cecilia...
Journal Article
‘One Friendly Flood’: Richard Crashaw’s Community of Strangers
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Caleb T Murray
Literature and Theology, Volume 31, Issue 4, December 2017, Pages 490–502, https://doi.org/10.1093/litthe/frx005
Published: 29 March 2017
... lyrical excess and its role in religious ecstasy, which is cast as the solitary fancy of the poet), this article analyses Crashaw’s content in light of his ‘fluid form’ in order to complicate an underlying assumption in Crashaw scholarship, namely, that ecstatic states are primarily solitary, typified...
Journal Article
Ecstasy (MDMA) Alters Cardiac Gene Expression and DNA Methylation: Implications for Circadian Rhythm Dysfunction in the Heart
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Christopher A. Koczor and others
Toxicological Sciences, Volume 148, Issue 1, November 2015, Pages 183–191, https://doi.org/10.1093/toxsci/kfv170
Published: 06 August 2015
..., please e-mail: [email protected] 2015 Abstract MDMA (ecstasy) is an illicit drug that stimulates monoamine neurotransmitter release and inhibits reuptake. MDMA’s acute cardiotoxicity includes tachycardia and arrhythmia which are associated with cardiomyopathy. MDMA acute cardiotoxicity has...
Journal Article
‘Ecstasy’ as a social drug: MDMA preferentially affects responses to emotional stimuli with social content
Margaret C. Wardle and others
Social Cognitive and Affective Neuroscience, Volume 9, Issue 8, August 2014, Pages 1076–1081, https://doi.org/10.1093/scan/nsu035
Published: 27 March 2014
..., and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected] Abstract 3,4-Methylenedioxymethamphetamine (MDMA, ‘ecstasy’) is used recreationally to improve mood and sociability, and has generated clinical interest as a possible...
Journal Article
The Mixture of “Ecstasy” and Its Metabolites Impairs Mitochondrial Fusion/Fission Equilibrium and Trafficking in Hippocampal Neurons, at In Vivo Relevant Concentrations
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Daniel José Barbosa and others
Toxicological Sciences, Volume 139, Issue 2, June 2014, Pages 407–420, https://doi.org/10.1093/toxsci/kfu042
Published: 04 March 2014
...: [email protected] 2014 Abstract 3,4-Methylenedioxymethamphetamine (MDMA; “ecstasy”) is a potentially neurotoxic recreational drug of abuse. Though the mechanisms involved are still not completely understood, formation of reactive metabolites and mitochondrial dysfunction contribute to MDMA-related...
Journal Article
MDMA enhances emotional empathy and prosocial behavior
Cédric M. Hysek and others
Social Cognitive and Affective Neuroscience, Volume 9, Issue 11, November 2014, Pages 1645–1652, https://doi.org/10.1093/scan/nst161
Published: 28 October 2013
...-Methylenedioxymethamphetamine (MDMA, ‘ecstasy’) releases serotonin and norepinephrine. MDMA is reported to produce empathogenic and prosocial feelings. It is unknown whether MDMA in fact alters empathic concern and prosocial behavior. We investigated the acute effects of MDMA using the Multifaceted Empathy Test (MET), dynamic...
Journal Article
Ecstacy-associated hyponatremia: why are women at risk?
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Michael L. Moritz and others
Nephrology Dialysis Transplantation, Volume 28, Issue 9, September 2013, Pages 2206–2209, https://doi.org/10.1093/ndt/gft192
Published: 26 June 2013
...Michael L. Moritz; Kamyar Kalantar-Zadeh; Juan Carlos Ayus Correspondence and offprint requests to: Juan Carlos Ayus; E-mail: [email protected] 28 2 2013 29 3 2013 © The Author 2013. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. 2013 ecstasy...
Journal Article
High incidence of mild hyponatraemia in females using ecstasy at a rave party
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Geetruida D. van Dijken and others
Nephrology Dialysis Transplantation, Volume 28, Issue 9, September 2013, Pages 2277–2283, https://doi.org/10.1093/ndt/gft023
Published: 08 March 2013
...-EDTA. All rights reserved. 2013 an increasingly common cause of hyponatremic encephalopathy in the outpatient setting is the use of the recreational drug ecstasy (3,4-methylenedioxymethamphetamine [MDMA]) FIGURE 1: Plasma sodium concentration of all participants. The plasma sodium concentration...
Journal Article
Disruption of prepulse inhibition by 3,4-methylenedioxymethamphetamine (MDMA): comparison between male and female wild-type and 5-HT1A receptor knockout mice
Maarten van den Buuse and others
International Journal of Neuropsychopharmacology, Volume 14, Issue 6, July 2011, Pages 856–861, https://doi.org/10.1017/S1461145711000101
Published: 01 July 2011
...Maarten van den Buuse; Thorsten Becker; Perrin Kwek; Sally Martin; Emma Ruimschotel; Victoria Risbrough The increased recreational use of the illicit drug, ‘Ecstasy’ (3,4-methylenedioxymethamphetamine; MDMA), and its potential detrimental long-term effects (Kalant, 2001 ) have sparked many...
Journal Article
Human Prostaglandin H Synthase (hPHS)-1 and hPHS-2 in Amphetamine Analog Bioactivation, DNA Oxidation, and Cytotoxicity
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Annmarie Ramkissoon and Peter G. Wells
Toxicological Sciences, Volume 120, Issue 1, March 2011, Pages 154–162, https://doi.org/10.1093/toxsci/kfq377
Published: 16 December 2010
... University Press on behalf of the Society of Toxicology. All rights reserved. For permissions, please email: [email protected] 2011 Abstract Neurotoxicity of the amphetamine analogs methamphetamine (METH) and 3,4-methylenedioxyamphetamine (MDA) (the active metabolite of ecstasy) may involve...
Journal Article
Case report of ecstasy-induced renal venous thrombosis
Mohamed Tarek Eldehni and others
NDT Plus, Volume 3, Issue 5, October 2010, Pages 459–460, https://doi.org/10.1093/ndtplus/sfq088
Published: 19 May 2010
...Mohamed Tarek Eldehni; Ian S.D. Roberts; Ramesh Naik; Emma Vaux Abstract The use of 3,4-methylenedioxymethamphetamine, also known as MDMA or ecstasy, has been associated with vascular and end-organ damage. This case report describes, with histological evidence, the development renal venous...
Journal Article
Decreased cerebral cortical serotonin transporter binding in ecstasy users: a positron emission tomography/[11C]DASB and structural brain imaging study
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Stephen J. Kish and others
in
Brain
Brain, Volume 133, Issue 6, June 2010, Pages 1779–1797, https://doi.org/10.1093/brain/awq103
Published: 17 May 2010
... that subjects used ecstasy on even a single occasion (e.g. McCann et al., 1998b ; Reneman et al., 2001 ; de Win et al., 2008a ; Selvaraj et al., 2009 ). This is a highly relevant concern as ecstasy users are often not aware of the drugs provided...
Journal Article
Ethanol increases the distribution of MDMA to the rat brain: possible implications in the ethanol-induced potentiation of the psychostimulant effects of MDMA
Sami Ben Hamida and others
International Journal of Neuropsychopharmacology, Volume 12, Issue 6, July 2009, Pages 749–759, https://doi.org/10.1017/S1461145708009693
Published: 01 July 2009
...Sami Ben Hamida; Antoine Tracqui; Anne Pereira de Vasconcelos; Esther Szwarc; Christine Lazarus; Christian Kelche; Byron C. Jones; Jean-Christophe Cassel 3,4-Methylenedioxymethamphetamine (MDMA or ecstasy) is a recreational drug which has reached high use among young people (Green et al...
Journal Article
S100B overexpressing mutant mice exhibit prolonged behavioural and biochemical responses towards repeated intermittent binge treatments with MDMA
Anna M. S. Kindlundh-Högberg and others
International Journal of Neuropsychopharmacology, Volume 12, Issue 2, March 2009, Pages 201–215, https://doi.org/10.1017/S1461145708009437
Published: 01 March 2009
... (MDMA; ‘ecstasy’) enhances serotonin and dopamine transmission. Repeated binge treatment with MDMA (5 mg/kg, 3 times daily, 3 h apart, once per week for 4 wk) was found to increase gene expression of S100B, a neurotrophic factor that modulates neuronal plasticity. Mutant mice overexpressing S100B were...
Journal Article
Sustained effects of ecstasy on the human brain: a prospective neuroimaging study in novel users
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Maartje M. L. de Win and others
in
Brain
Brain, Volume 131, Issue 11, November 2008, Pages 2936–2945, https://doi.org/10.1093/brain/awn255
Published: 07 October 2008
...Maartje M. L. de Win; Gerry Jager; Jan Booij; Liesbeth Reneman; Thelma Schilt; Cristina Lavini; Sílvia D. Olabarriaga; Gerard J. den Heeten; Wim van den Brink A cohort of 188 ecstasy-naive young adults (77 males, 111 females, 21.7 ± 3.0 year) with a relatively high probability of starting to use...
Journal Article
Ecstasy produces left ventricular dysfunction and oxidative stress in rats
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Sylvia K. Shenouda and others
Cardiovascular Research, Volume 79, Issue 4, 1 September 2008, Pages 662–670, https://doi.org/10.1093/cvr/cvn129
Published: 20 May 2008
[email protected] 2008 Abstract Aims Our aim was to determine whether the repeated, binge administration of 3,4-methylenedioxymethamphetamine (ecstasy; MDMA) produces structural and/or functional changes in the myocardium that are associated with oxidative stress. Methods and results Echocardiography...
Journal Article
Acute toxic effects of ‘Ecstasy’ (MDMA) and related compounds: overview of pathophysiology and clinical management
A. P. Hall and J. A. Henry
BJA: British Journal of Anaesthesia, Volume 96, Issue 6, June 2006, Pages 678–685, https://doi.org/10.1093/bja/ael078
Published: 04 April 2006
...A. P. Hall; J. A. Henry An association between Ecstasy use and cerebral haemorrhage, cerebral venous sinus thrombosis, and aplastic anaemia has been reported. 18 26 33 37 56 There have also been a number of reports of pneumothorax and pneumomediastinum in Ecstasy users. 3 39 53 In one...
Journal Article
Acute and long-term effects of a single dose of MDMA on aggression in Dark Agouti rats
Eszter Kirilly and others
International Journal of Neuropsychopharmacology, Volume 9, Issue 1, February 2006, Pages 63–76, https://doi.org/10.1017/S146114570500581X
Published: 01 February 2006
... is a requirement, aggressive behaviour and acute anti-aggressive effects of MDMA and 5-HT1B receptor agonists remain intact 3 wk after a single dose of the drug despite significant damage to the serotonergic system. Aggression ecstasy local cerebral metabolic rate of glucose utilization 5...
Journal Article
Hyponatraemia and seizures after ecstasy use
Simon B Holmes and others
Postgraduate Medical Journal, Volume 75, Issue 879, January 1999, Pages 32–34, https://doi.org/10.1136/pgmj.75.879.32
Published: 01 January 1999
...Simon B Holmes; Anindo K Banerjee; William D Alexander A 26-year-old man was admitted to hospital after a seizure at home. He had ingested one tablet of ecstasy 6 hours prior to the onset of the seizures. In keeping with popular practice, he had consumed a large volume of water along...
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