... to conventional glucocorticoids. Glucocorticoid-sparing therapies such as crinecerfont and atumelnant offer the potential for a block-and-replace strategy, with physiologic replacement dosing of hydrocortisone. Clinical Trial Registration None. congenital adrenal hyperplasia 21-hydroxylase deficiency drug...

.... Achieving these effects in this short period for a disorder with significant burden and treatment limitations is of great interest. Tehran University of Medical Sciences 10.13039/501100004484 57532 combination drug therapy neuroimmunomodulation psychosis psychotic disorder randomized controlled...

..., and reproduction in any medium, provided the original work is properly cited. ABSTRACT Background Kidney complications associated with anticancer drug therapy have greatly increased recently. We aimed to investigate the real-world clinical outcomes of anticancer drug therapy–associated renal complications...

... resistance whole-genome sequencing drug therapy Fluoroquinolone resistance was present in 0.8% of isolates with DS TB (n = 91 of 11 198), 1.1% of isolates with isoniazid monoresistance (n = 8 of 711), 4.2% of isolates with RR TB (n = 3 of 72), and 23.9% of MDR-TB isolates with resistance to both...

... Graphical Abstract COVID-19 drug therapy symptoms nirmatrelvir ritonavir EPIC-HR Pfizer Inc 10.13039/100004319 More than 775 million cumulative cases and 7.0 million deaths from coronavirus disease 2019 (COVID-19) have been reported globally [ 1 ]. The US Centers for Disease Control and Prevention...

.... Obesity is most prevalent among non-Hispanic Black adults (49.9%), followed by Hispanic adults (45.6%), non-Hispanic White adults (41.4%), and non-Hispanic Asian adults (16.1%). ⁵ endocrinology new drug therapy obesity pharmacotherapy weight loss Abstract Purpose This review summarizes...

... therapeutic goals. Integrated health-system specialty pharmacies are integrated into the care team and provide advanced monitoring capabilities, making them an ideal setting for managing ultra-complex specialty medications. clinical pharmacy services drug therapy management specialty pharmacy Abstract...

... interruption. However, there are no clear guidelines regarding the safe timing for restarting chemotherapy. We conducted a retrospective study to assess when such patients can safely recommence chemotherapy. Of the 40 patients included in this study, 34 restarted anticancer drug therapy after COVID-19...

... humans carcinoma ovarian epithelial/drug therapy female Dutch Cancer Society IKNL2014-6838 Kom Op Tegen Kanker—The Flemish Cancer Society 3M150511 Ovarian cancer is the deadliest gynecological malignancy in Western countries, ¹ with high-grade serous (HGSOC) being the most...

... within the context of ERPs. As such, any pharmacist should feel empowered to aid in the care of surgical patients. bariatric surgery clinical pharmacist drug therapy minimally invasive surgical procedures As enhanced recovery pathways (ERPs) have been integrated into surgical practices, pharmacists...

... of uncomplicated GD and its variants, as well as the response to persistent and recurrent hyperthyroidism. Graves disease hyperthyroidism thyroid eye disease antithyroid drug therapy radioiodine therapy pregnancy Graves disease (GD) is an autoimmune disease and is the most common form of hyperthyroidism ( 1...

...Rachel M Wake; Phoebe E Allebone-Salt; Larissa L H John; Ben A Caswall; Nelesh P Govender; Ronen Ben-Ami; Lyle W Murray; Clare Logan; Thomas S Harrison; Tihana A Bicanic Candida auris candidiasis combination drug resistance drug therapy Correspondence: Rachel M. Wake, BSc, BM, MRCP...

... effective for treatment. Results were consistent between bacteremic and nonbacteremic illness. fluoroquinolone/therapeutic use treatment outcome tularemia/drug therapy computed tomography X ray Research and Development Unit Region Jämtland-Härjedalen and Region Västerbotten Inhalation...

... combined chemoimmunotherapy in a real‐world setting. ramucirumab docetaxel non-small-cell lung carcinoma combined drug therapy VEGF-A VEGF-D Implications for Practice The application of combined chemoimmunotherapy exhibits improved outcomes for patients with advanced non-small-cell lung cancer...

... to the inhibition of the EGFR/JNK/c-JUN signaling pathway. This result suggests that EC has potential to be developed as an antifungal sensitizer to treat OPC caused by azole-resistant C. albicans. ethyl caffeate combination drug therapy azole-resistant C. albicans oropharyngeal candidiasis...

... to declare. TRIAL REGISTRATION NUMBER The trial is not registered at any trial registry. endometriosis endometriosis drug therapy social media free-word association endometriosis survey Endometriosis is a chronic inflammatory, oestrogen-dependent disease affecting women of reproductive age...

... that provide early benefit. Some other anti-inflammatory or antifibrotic drugs may potentially control the FS, but have not been proven effective in the clinical setting. Future studies should be targeted to develop steroid-sparing agents that inhibit biological events in FS. Drug therapy fibrosis frozen...

... productivity. Patients reporting impacted productivity and those taking certain DMTs may require more frequent pharmacist actions. disease management hospital pharmacy service multiple sclerosis/drug therapy patient-reported outcome measures specialty pharmacy pharmacists Key Points Health-system...

...Andrés F Henao-Martínez; Michaele Francesco Corbisiero; Ixchel Salter; Daniel B Chastain; George R Thompson Aspergillus invasive pulmonary aspergillosis mortality drug therapy We captured the treatment pathways within the TriNetX platform for all patients diagnosed with IPA (B44.0...

... of at least 3 months. Graphical Abstract Graphical Abstract combination drug therapy cyclosporine idiopathic membranous nephropathy mycophenolate mofetil steroid Beijing Municipal Administration of Hospitals Incubating Program PX2022003 Capital Medical University 10.13039/501100002799...