... of neuropathogenesis in the developing fetal brain are incompletely understood. Animal models biologically representative of congenital infection have been used to characterize the effects of cCMV on neurogenesis, brain development, and cochlear development. Murine models utilizing host transcriptional analyses have...

... definitive associations. This review summarizes macaque models of prenatal and postnatal Zika virus infection. Vision and motor domains are the most common developmental deficits and may be associated with maternal viral RNAemia duration. Zika virus neurodevelopment behavior congenital infection nonhuman...

.... The detection of DNAemia would be helpful in assessing risk of intrauterine transmission. cytomegalovirus congenital infection pregnant woman serology virology Potential conflicts of interest. All authors: No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure...

...-with-valaciclovir-following-infection-in-early-pregnancy valaciclovir cytomegalovirus prevention congenital cytomegalovirus congenital infection pregnancy Cytomegalovirus (CMV) is the most frequent cause of congenital viral infection. The risk of serious sequelae is greatest when primary maternal infection...

... Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Cytomegalovirus is now the most common cause of congenital infections, leading to numerous abnormalities. After 50 years of failed attempts to develop a licensed vaccine to be given to women before pregnancy...

... 204870/Z/16/Z Human cytomegalovirus (HCMV; species Human betaherpesvirus 5) causes serious disease in transplant recipients and people with immune deficiencies and is a leading cause of congenital infection worldwide ( Manicklal et al. 2013 ). Licensed vaccines are not yet available...

... infection nonprimary infection preconception immunity Fondazione Regionale per la Ricerca Biomedica 10.13039/501100022720 FRRB 2015-0043 In developed countries, human cytomegalovirus (HCMV) is the leading cause of congenital infections, which may result in neurocognitive and psychomotor delay, hearing...

... and paired maternal-infant non-treponemal titres at birth are not sensitive for diagnosing CS. Serologies can be falsely negative with recent infection. Regardless of investigations or clinical findings, 10 days of intravenous penicillin G should be considered for all high-risk infants. Congenital...

... retardation and visceral damage to the liver, causing hepatocellular damage and hemosiderosis. To the best of our knowledge, this is the first report in the literature of fetal demise secondary to maternal–fetal transmission of SARSCoV- 2 with a congenital infection and a pathological description of placental...

...: [email protected]. 2021 This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) congenital infection vaccine hesitancy...

... antibody levels to key epitopes on cytomegalovirus pentamer, comparing mothers who transmitted cytomegalovirus to their fetuses to mothers who did not. We found higher antibody levels in the transmitters, providing evidence for antibody boosting but not protection. congenital infection cytomegalovirus...

... This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Babesia microti babesiosis congenital babesiosis congenital...

... charge des nouveau-nés infectés. Il est essentiel d’adopter une prise en charge multidisciplinaire pour optimiser le pronostic des nouveau-nés atteints. Congenital infection Cytomegalovirus (CMV) Neurodevelopmental sequelae Polymerase chain reaction (PCR) Sensorineural hearing loss (SNHL...

...Michelle Barton; A Michael Forrester; Jane McDonald Abstract Cytomegalovirus (CMV) is the leading cause of congenital infection and the most common cause of non-genetic sensorineural hearing loss (SNHL) in childhood. Although most infected infants are asymptomatic at birth, the risk for SNHL...

... section. Overall, 58 neonates were reported with SARS-CoV-2 infection (4 had a congenital infection), of which 29 (50%) were symptomatic (23 required ICU) with respiratory symptoms being the predominant manifestation (70%). No mortality was reported in SARS-CoV-2-positive neonates. Conclusion...

... virus vertical transmission can occur earlier in pregnancy. measles placenta pregnancy congenital infection Data regarding measles placental infection are limited to the single observation of viral particles in syncytiotrophoblasts in 1 placenta [ 13 ]. Here, we confirm the presence of viral RNA in 2...

... prevent transmission from mother to fetus or reduce severity of disease in affected infants. More effective prevention and treatment approaches are needed, informed by a deeper understanding of the mechanisms that underly CMV transmission and of virus–host interactions during early congenital infection. T...

... of cytomegalovirus infection with valganciclovir: review of the literature . Med Microbiol Immunol 2017 ; 206 : 347 – 54 . Abstract Cytomegalovirus (CMV) is the most common congenital infection and infectious cause of fetal anomaly and neurologic injury. However, treatment strategies for congenital CMV (cCMV...

... in a Brazilian population with 98% maternal seroprevalence rate in which 90% of the congenital infections were associated with nonprimary infections in approximately 2000 women-infant pairs observed from first trimester gestation until 1 month after delivery [ 10 ]. Taken these data together, as outlined...

...Nazia Kabani; Shannon A Ross As noted, the majority of infants with cCMV are asymptomatic at birth, thus they will not be identified as congenitally infected in the newborn period. Because approximately half of hearing loss in asymptomatic children is delayed [ 19 ], screening for cCMV...