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Keywords: Whipple’s disease
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Journal Article

Susceptibility of nucleotide-binding oligomerization domain 2 mutations to Whipple’s disease

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Katrina A Williamson and others
Rheumatology, Volume 63, Issue 5, May 2024, Pages 1291–1296, https://doi.org/10.1093/rheumatology/kead372
Published: 19 July 2023
... of Rheumatology, Mayo Clinic, Mayo Building, 15th Floor East 200 First St. SW Rochester, MN 55905,  USA. E-mail: [email protected] Abstract Objectives Whipple’s disease (WD) results from infection of the bacteria Tropheryma whipplei (TW). This disease is characterized by macrophage infiltration...
Journal Article

Tropheryma whipplei Endocarditis: Case Presentation and Review of the Literature

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Michael McGee and others
Open Forum Infectious Diseases, Volume 6, Issue 1, January 2019, ofy330, https://doi.org/10.1093/ofid/ofy330
Published: 07 December 2018
... unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Whipple’s disease is a rare infective condition, classically presenting with gastrointestinal manifestations. It is increasingly recognized as an important cause of culture-negative...
Journal Article

Potential Role for Urine Polymerase Chain Reaction in the Diagnosis of Whipple’s Disease

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Annette Moter and others
Clinical Infectious Diseases, Volume 68, Issue 7, 1 April 2019, Pages 1089–1097, https://doi.org/10.1093/cid/ciy664
Published: 22 October 2018
... Control group of healthy volunteers, n = 40 Untreated 14/26 20–73, 42 ± 14 5/40, 12.5% 0/40, 0.0% Abbreviations: DNA, deoxyribonucleic acid; SD, standard deviation; T. whipplei, Tropheryma whipplei; WD, Whipple’s disease. a As detected by T. whipplei–specific...
Journal Article

Deep jaundice in an adolescent

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M Deutsch and others
Postgraduate Medical Journal, Volume 79, Issue 935, September 2003, Page 544, https://doi.org/10.1136/pmj.79.935.544
Published: 17 September 2003
... University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Whipple’s disease Tropheryma whippelii jaundice Epstein-Barr cholestasis haemolysis infectious mononucleosis Answers on p 548 . A 16 year old girl, previously...
Journal Article

Whipple’s disease

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Ranjit N Ratnaike
Postgraduate Medical Journal, Volume 76, Issue 902, December 2000, Pages 760–766, https://doi.org/10.1136/pmj.76.902.760
Published: 01 December 2000
... ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) It is estimated that Whipple’s disease has occurred in 1500–2000 patients, 11 predominantly in middle aged white males. 12 More recent data identify a somewhat older age group: in 52 patients with Whipple’s...
Journal Article

Symptomatic cardiomyopathy as a presentation in Whipple’s disease

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P G de Takats and others
Postgraduate Medical Journal, Volume 71, Issue 834, April 1995, Pages 236–239, https://doi.org/10.1136/pgmj.71.834.236
Published: 01 April 1995
... which led to the diagnosis of Whipple’s disease, associated with dilated cardiomyopathy. Conventional antibiotic therapy for Whipple’s disease resulted in resolution of the traditional features of Whipple’s disease and a marked improvement in the patient’s heart failure. Whipple’s disease dilated...
Journal Article

Xanthogranulomatous Pseudotumor of the Vagina: Evidence of a Local Response to an Unusual Bacterium (Mucoid Escherichia coli) Get access

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Susan M. Strate and others
American Journal of Clinical Pathology, Volume 79, Issue 5, 1 May 1983, Pages 637–643, https://doi.org/10.1093/ajcp/79.5.637
Published: 01 May 1983
... of this case in terms of defective defective clearance of bacteria from a variety of tissues. (Key bacterial processing and relate it to morphologically sim• words: Xanthogranulomatous inflammation; Malakoplakia; Mucoid E. coli; Vagina; Whipple's disease; Pseudotumor) Am ilar diseases such as Whipple's...
Journal Article

Constrictive pericarditis and intestinal haemorrhage due to Whipple’s disease

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T Crake and others
Postgraduate Medical Journal, Volume 59, Issue 689, March 1983, Pages 194–195, https://doi.org/10.1136/pgmj.59.689.194
Published: 01 March 1983
... a bleeding site related to an area of abnormal vasculature in the caecum. At laparotomy, the small bowel was found to be inflamed and the mesenteric lymph nodes enlarged. The overall histological appearances, confirmed later on endoscopic duodenal biopsies, were those of Whipple’s disease. His symptoms...
Journal Article

Cerebral Whipple’s Disease. Diagnosis by Brain Biopsy Get access

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Lewis Johnson and Israel Diamond
American Journal of Clinical Pathology, Volume 74, Issue 4, 1 October 1980, Pages 486–490, https://doi.org/10.1093/ajcp/74.4.486
Published: 01 October 1980
... Whipple’s disease, a multisystem chronic granulomatous disease treatable by antibiotics, usually presents clinically with gastrointestinal or joint symptoms. Usually, the diagnosis is substantiated by small intestinal biopsy. This shows diastase-resistant periodic-acid-Schiff- (PAS)-positive inclusions...
Journal Article

Bacillary Bodies in Whipple’s Disease Get access

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Jan Piťha
American Journal of Clinical Pathology, Volume 67, Issue 2, 1 February 1977, Page 200, https://doi.org/10.1093/ajcp/67.2.200
Published: 01 February 1977
...Jan Piťha Address reprint requests to Dr. Pitha. 21 09 1976 28 09 1976 © American Society of Clinical Pathologists 1977 Intestinal lipodystrophy Whipple’s disease Heart Central nervous system 200 LETTERS TO THE EDITOR A.J.C.I...
Journal Article

Pancarditis in Whipple’s Disease: Electronmicroscopic Demonstration of Intracardiac Bacillary Bodies Get access

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J. T. Lie and J. S. Davis
American Journal of Clinical Pathology, Volume 66, Issue 1, 1 July 1976, Pages 22–30, https://doi.org/10.1093/ajcp/66.1.22
Published: 01 July 1976
...J. T. Lie; J. S. Davis Pancarditis in Whipple's Disease Electronmicroscopic Demonstration of Intracardiac Bacillary Bodies J. T. LIE, M.D., AND J. S. DAVIS, M.D. From the Departments...
Chapter

Nystagmus Get access

Agnes M F Wong
in Eye Movement Disorders
Published: 15 May 2008
... with similar amplitude and frequency. ■ Disconjugate: Both eyes move in the same direction with different amplitude and frequency (e.g., internuclear ophthalmoplegia). ■ Disjunctive: The eyes move in opposite directions (e.g., oculomasticatory myorhythmia seen in Whipple’s disease). Alexander’s law Brun’s...
Chapter

Whipple’s disease and sprue Get access

Amirkaveh Mojtahed and Payam Afshar
in Schlossberg's Clinical Infectious Disease (3 edn)
Published: 01 October 2021
...Oxford University Press This chapter examines Whipple’s disease and tropical sprue. Whipple’s disease is primarily a disease of the gastrointestinal tract with extra-intestinal symptoms of arthralgia, fever, and neurologic syndromes. The nonspecific clinical presentation of the condition creates...
Chapter

Other dyskinetic syndromes Get access

Mark J. Edwards and others
in Parkinson's Disease and other Movement Disorders (2 edn)
Published: 01 January 2016
... encephalitis. hemifacial spasm hyperkinetic hemi-masticatory spasm painful legs and moving toes oculo-masticatory myorhythmia Whipple’s disease botulinum toxin botulinum toxin treatment hemifacial spasm idiopathic hemifacial spasm surgical treatment facio brachial dystonic seizures hemi masticatory...
Chapter

Disorders of Ocular Motility Due to Disease of the Brainstem, Cerebellum, and Diencephalon Get access

R. John Leigh and David S. Zee
in The Neurology of Eye Movements (5 edn)
Published: 01 June 2015
... affecting the rostral interstitial nucleus of the medial longitudinal fasciculus (RIMLF), interstitial nucleus of Cajal, posterior commissure, and more diffuse processes causing slow vertical saccades or vertical gaze palsy (dorsal midbrain syndrome), including Whipple’s disease. Effects of lesions...
Chapter

Whipple’s Disease Get access

Don Gilden
in Neuroinfections (1)
Published: 01 April 2013
...Oxford University Press Whipple’s disease is characterized by dementia, ophthalmoplegia (usually vertical), and myoclonus. Whipple’s disease has a predilection for the high brain stem, hypothalamus, and medial temporal lobe, usually seen as increased signal on MRI. Whipple’s disease also affects...
Chapter

Whipple’s disease Get access

Florence Fenollar and Didier Raoult
in Oxford Textbook of Medicine (6 edn)
Published: 01 January 2020
...Oxford University Press Whipple’s disease is an uncommon infection caused by the actinomycete Tropheryma whipplei, most commonly diagnosed when overt small intestinal disease leads to malabsorption, but with protean other clinical manifestations (e.g. systemic, neurological...
Chapter

Miscellaneous conditions presenting to the rheumatologist Get access

Stuart Carter and others
in Oxford Textbook of Medicine (6 edn)
Published: 01 January 2020
... tendinopathy, drug-induced lupus, and allopurinol hypersensitivity). miscellaneous infections Whipple’s disease chikungunya Syill’s disease Charcot joint Tietze’s syndrome adult onset Still’s disease AOST C reactive protein CRP erythrocyte sedimentation rate ESR rheumatological diseases skin diseases...
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Neurological Manifestations of Gastrointestinal and Hepatic Diseases Get access

Brian P. Bosworth and others
in Neurobiology of Disease (2 edn)
Published: 01 August 2016
... bowel disease Whipple’s disease Wilson’s disease acute intermittent porphyria iron overload CNS vasculitis Alimentary tract diseases Celiac disease Gastrointestinal diseases Cerebellar ataxia Gluten ataxia Depression Epilepsy Headache Migraine Myopathy Neuropathy Tension type headache...
Chapter

Gastroenterology Get access

Donna B. Greenberg
in Psychiatric Care of the Medical Patient (3 edn)
Published: 01 June 2015
.... C. , & Higginbottom, P. A. ( 2010 ). Whipple’s disease: A rare disease revisited.   Current Gastroenterology Reports , 12, 263–269. 10.1007/s11894-010-0110-7 20532708 Akil, M. , & Brewer, G. J. ( 1995 ). Psychiatric and behavioral...