... (HBs) are biologically benign, their management is often complicated, particularly in the context of von Hippel–Lindau disease (VHL). Few studies have investigated treatment outcomes of both VHL-related sporadic HBs in detail. This study assessed the clinical characteristics and neurosurgical outcomes...

..., The magnetic resonance imaging (MRI) of the head. The arrows show the lesion in bilateral cerebellar bulbar cisterna. C, The magnetic resonance imaging (MRI) of the thoracic vertebrae. The arrows show the lesion in the thoracic vertebrae. Pituitary adenomas rarely occur in the setting of von Hippel-Lindau...

... otherwise healthy individuals with “incidental” Von Hippel Lindau (VHL) disease. These patients were found to have pathogenic germline variants in the VHL gene, after undergoing genetic testing for other purposes (5 for familial breast cancer risk and 1 to determine ancestry) but no VHL disease...

... Graphical Abstract complete resection multicenter study neurological outcomes progression-free survival spinal hemangioblastomas von Hippel–Lindau disease Johannes Wach and Alim Emre Basaran contributed equally to this work...

... RH , Glasker S . The first prospective trial for Von Hippel-Lindau disease: pazopanib . Lancet Oncol 2018 ; 19 : 1267 – 9 . 10.1016/S1470-2045(18)30533-3 . 5. Zamarud A , Marianayagam NJ , Park DJ , et al. The outcome of central nervous system hemangioblastomas...

.... The majority of these tumors are nonmetastatic, with complete cure achieved through surgical resection. PPGLs have been associated with several hereditary cancer syndromes, including von Hippel-Lindau (VHL). We present the case of a 10-year-old patient with VHL and a history of 2 asynchronous pheochromocytomas...

..., pancreatic cysts, and a renal cyst. The endocrinology service was consulted for possible PCCs associated with von Hippel-Lindau disease (VHL). Serum and urine normetanephrine levels were elevated despite the lack of overt PCCs/PGLs seen on magnetic resonance imaging and magnetic resonance angiography...

...-rights ) Abstract Context Von Hippel-Lindau disease (VHL) is a rare, autosomal-dominant hereditary cancer-predisposition syndrome caused by germline pathogenic variants (PVs) in the VHL gene. It is associated with a high penetrance of benign and malignant vascular tumors in multiple organs...

... service via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract Background von Hippel-Lindau disease (VHL) is an autosomal dominant familial neoplasia syndrome. The most common manifestation of VHL is central nervous system...

...) is an uncommon, benign, non-meningothelial, mesenchymal tumour of unclear origin. Most are associated with von Hippel-Lindau (VHL) syndrome (71%), and only 40 cases have been reported in the medical literature. Most of the patients develop non-specific visual symptoms, including decreased visual acuity...

...-specific MTR percentiles 5th, 25th, 50th, and neutrality. Corresponding author. D.B.A. Chemistry Building 68, Cooper Road, The University of Queensland, St Lucia, QLD 4067, Australia. E-mail: [email protected] . Von Hippel-Lindau VHL clear cell renal cell carcinoma ccRCC machine learning National...

... and the Purkinje layer to form the molecular layer ( 28 ). von Hippel-Lindau (VHL) disease is an autosomal dominant hereditary cancer disorder, affecting approximately 1 in 35 000 persons ( 1 ). These patients inherit one dysfunctional copy of the VHL tumor suppressor gene (3p25-26), rendering them...

... flow and timing were regarded as unclear, because only 23 out of 28 VHL patients were analyzed for the biomarkers VIP and PP. Characteristics of all included studies can be found in Table 4 . Von Hippel-Lindau (VHL) disease is a genetic disorder characterized by the growth of cysts and tumors...

... tumors that can be sporadic or multiple, as part of Von Hippel-Lindau disease. They develop at any level of the central nervous system, with a predilection for the dorsal medulla among brainstem locations. Radical resection of the solid portion of the tumor is the best treatment option. ^{1 , 2}...

...Reinier Alvarez; Panagiotis Mastorakos; Elizabeth Hogan; Gretchen Scott; Russell R Lonser; Henry E Wiley; Emily Y Chew; Prashant Chittiboina Optic nerve hemangioblastoma von Hippel-Lindau Retrobulbar hemangioblastoma ABBREVIATIONS CNS central nervous system HGB hemangioblastomas IM...

... suppressor genes (eg, the gene encoding von Hippel-Lindau [VHL] tumor suppressor protein) can activate tumorigenesis even with normal levels of oxygen, providing support for the notion that the HIF-VHL-VEGF axis is amenable to targeted therapies for the treatment of RCC. This article highlights the current...

... under the terms of the Creative Commons Attribution Non-Commercial, No-Derivatives License (CC BY-NC-ND; https://creativecommons.org/licenses/by-nc-nd/4.0/ ). Abstract Context Von Hippel-Lindau (VHL) disease is an autosomal dominant syndrome caused by germline mutations in the VHL gene...

..., Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) von hippel -lindau disease dysphagia hemangioblastoma pheochromocytoma syrinx A 25-year-old man presented with 2-week history of progressively worsening dysphagia to solids and liquids...

... Journals Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Abstract This 3-dimensional operative video illustrates resection of a thoracic hemangioblastoma in a 30-year-old female with a history of Von Hippel-Lindau disease...

... is properly cited. For commercial re-use, please contact [email protected] Abstract This video demonstrates the microsurgical resection of brainstem hemangioblastoma. The patient is a 32-yr-old woman with Von Hippel Lindau syndrome who presented with quadriparesis and inability to swallow...