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Keywords: Disease
Journal Article
Genome-wide Evidence of Host Specialization in Wild and Farmland Populations of the Fungal Leaf Spot Pathogen, Cercospora beticola
Genome Biology and Evolution, Volume 17, Issue 4, April 2025, evaf053, https://doi.org/10.1093/gbe/evaf053
Published: 28 April 2025
... of novel pathogens, which may spread across large geographical distances with their crop host. In this study, we addressed the recent evolution of the fungal pathogen causing the disease Cercospora leaf spot, Cercospora beticola. This pathogen has become increasingly important in sugar...
Journal Article
ACCEPTED MANUSCRIPT
Growth hormone replacement in craniopharyngioma: analysis of the Hypopituitary Control and Complications Study (HypoCCS)
Journal of the Endocrine Society, bvaf072, https://doi.org/10.1210/jendso/bvaf072
Published: 28 April 2025
... (HypoCCS), a global prospective surveillance study of adult GH replacement, to assess the impact of GH replacement on metabolic outcomes in adult-onset CP. Methods Primary outcome was a composite endpoint of adverse hepatic outcomes including metabolic dysfunction-associated steatotic liver disease...
Journal Article
Bilateral pneumothorax following acupuncture
Oxford Medical Case Reports, Volume 2025, Issue 4, April 2025, omaf015, https://doi.org/10.1093/omcr/omaf015
Published: 28 April 2025
... and good lung re-expansion. The drains were removed four days later, and the patient was discharged. acupuncture therapy iatrogenic disease pneumothorax Pneumothorax is a complication associated with acupuncture and can result from acupuncture of the chest, supraclavicular fossa, or dorsum [ 1...
Journal Article
ApoB-containing lipoproteins: count, type, size, and risk of coronary artery disease
European Heart Journal, ehaf207, https://doi.org/10.1093/eurheartj/ehaf207
Published: 28 April 2025
... for coronary artery disease (CAD) remains unclear. Methods A prospective analysis of 207 368 UK Biobank participants with comprehensive lipoprotein profiling and no prior history of atherosclerotic disease, diabetes, or active lipid-lowering therapy was conducted. Multivariable-adjusted Cox regression...
Journal Article
ACCEPTED MANUSCRIPT
Biventricular Reverse Remodelling Achieved through Combined Surgical and Optimal Medical Therapy in an Adolescent Female Post-Rastelli Procedure: A Case Report
European Heart Journal - Case Reports, ytaf215, https://doi.org/10.1093/ehjcr/ytaf215
Published: 28 April 2025
... disease patients to reach adulthood, resulting in an increase in adult congenital heart disease (ACHD) cases. Managing heart failure (HF) in ACHD patients is a significant concern, particularly due to limited understanding of optimal pharmacological therapies. Conduit dysfunction and right heart failure...
Journal Article
STING: a multifaced player in cellular homeostasis Get access
Human Molecular Genetics, ddae175, https://doi.org/10.1093/hmg/ddae175
Published: 28 April 2025
...-rights ) Abstract The st imulator of in terferon g ene (STING) is an important innate immune mediator of the cytoplasmic DNA sensing pathway. As a mediator known for its role in the immune response to infections, STING is also surprisingly at the center of a variety of non-infectious human diseases...
Journal Article
Leukocytoclastic Vasculitis in IL-12RB1 deficiency: a rare manifestation of Mendelian susceptibility to mycobacterial disease
Oxford Medical Case Reports, Volume 2025, Issue 4, April 2025, omaf069, https://doi.org/10.1093/omcr/omaf069
Published: 28 April 2025
.../by-nc/4.0/ ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected] Abstract Mendelian susceptibility to mycobacterial disease (MSMD) is a rare genetic condition...
Journal Article
ACCEPTED MANUSCRIPT
Underestimation of Cardiovascular Risk by the SCORE2 Model in Primary Care: A Call for Recalibration
European Journal of Preventive Cardiology, zwaf253, https://doi.org/10.1093/eurjpc/zwaf253
Published: 27 April 2025
... on the estimated risk, many patients might not receive the treatment they need based on this model alone. Graphical Abstract Graphical Abstract SCORE2 Risk of Cardiovascular Disease Primary Prevention ACCEPTED MANUSCRIPT 1 Underestimation of Cardiovascular Risk by the SCORE2 Model in 2 Primary Care: A Call...
Journal Article
Spatiotemporal regulation of neutrophil heterogeneity in health and disease Get access
Human Molecular Genetics, ddaf008, https://doi.org/10.1093/hmg/ddaf008
Published: 27 April 2025
...-rights ) Abstract Neutrophils are the most abundant leukocytes in humans and are indispensable for innate immunity. They are short-lived, terminally differentiated cells. However, mounting evidence indicates that neutrophils are heterogeneous in health and disease: they are young or aged in a steady...
Journal Article
ACCEPTED MANUSCRIPT
Gross total resection is associated with improvement and prognosis even in von Hippel–Lindau disease-related hemangioblastomas: Nationwide registry in Japan Get access
Neuro-Oncology Practice, npaf042, https://doi.org/10.1093/nop/npaf042
Published: 27 April 2025
... (HBs) are biologically benign, their management is often complicated, particularly in the context of von Hippel–Lindau disease (VHL). Few studies have investigated treatment outcomes of both VHL-related sporadic HBs in detail. This study assessed the clinical characteristics and neurosurgical outcomes...
Journal Article
Transcriptional reprogramming in SMA mouse hearts reveals signatures of early heart failure and dysregulated calcium signaling Get access
Human Molecular Genetics, ddaf060, https://doi.org/10.1093/hmg/ddaf060
Published: 27 April 2025
... Published by Oxford University Press 2025. 2025 This work is written by US Government employees and is in the public domain in the US. Abstract Spinal muscular atrophy (SMA) is an inherited neurodegenerative disease that leads to loss of motor neurons in the anterior horn of the spinal cord...
Journal Article
ACCEPTED MANUSCRIPT
A rare variant of anomalous left coronary artery from pulmonary artery (ALCAPA) syndrome: Images in cardiology
European Heart Journal - Case Reports, ytaf206, https://doi.org/10.1093/ehjcr/ytaf206
Published: 26 April 2025
... distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. case report congenital heart disease coronary angiography...
Journal Article
ACCEPTED MANUSCRIPT
Life’s Essential 8 and progression of cardiometabolic multimorbidity trajectory: a prospective study of UK Biobank Get access
European Journal of Preventive Cardiology, zwaf247, https://doi.org/10.1093/eurjpc/zwaf247
Published: 26 April 2025
... (median age, 57 years) free of CMDs at baseline from the UK Biobank. LE8 scores were divided into low, moderate, and high cardiovascular health (CVH) groups at baseline, with higher LE8 scores representing better CVH. CMM was defined as the coexistence of two or three cardiometabolic diseases, including...
Journal Article
Presenilin 1 M139I mutation regulates the microRNA-34a-mediated neurogenic locus notch homolog protein 1 signaling pathway in an early-onset Alzheimer disease cell model Get access
Journal of Neuropathology & Experimental Neurology, nlaf044, https://doi.org/10.1093/jnen/nlaf044
Published: 26 April 2025
.../standard-publication-reuse-rights ) Abstract Presenilin 1 (PSEN1) mutations are the leading cause of early-onset Alzheimer disease (EOAD). A recent study found that the PSEN1 M139I mutation is associated with EOAD. In this study, we examined the impact of the PSEN1 M139I mutation in an EOAD in vitro model...
Journal Article
Hyperthyroidism From Graves Disease Relapsed as Hot Nodule
JCEM Case Reports, Volume 3, Issue 6, June 2025, luaf074, https://doi.org/10.1210/jcemcr/luaf074
Published: 25 April 2025
... reuse, distribution, and reproduction in any medium, provided the original work is properly cited. See the journal About page for additional terms. hyperthyroidism Graves disease toxic nodular goiter radioactive iodine uptake thyroid nodule A 70-year-old female presented with hyperthyroidism from...
Journal Article
ACCEPTED MANUSCRIPT
Reply to Papazisi et al Get access
European Journal of Cardio-Thoracic Surgery, ezaf096, https://doi.org/10.1093/ejcts/ezaf096
Published: 25 April 2025
...-reuse-rights ) tricuspid annuloplasty tricuspid regurgitation tricuspid valve repair valvular heart disease right heart failure ACCEPTED MANUSCRIPT Reply to Papazisi et al. Authors: Yoshikazu Ono, MD, Shin Yajima, MD, Tomoyuki Fujita, MD, and Satsuki Fukushima, MD Institution: Department...
Journal Article
ACCEPTED MANUSCRIPT
Temporal trends in patient demographics and kidney outcomes in cardiac surgery: a regional danish follow-up study Get access
European Journal of Cardio-Thoracic Surgery, ezaf144, https://doi.org/10.1093/ejcts/ezaf144
Published: 25 April 2025
... Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract OBJECTIVES Chronic kidney disease can develop as a long-term complication after cardiac surgery–a condition associated with increased risk of new cardiovascular events, readmissions, and mortality...
Journal Article
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Aortic arch configurations according to reconstruction methods following the norwood procedure for hypoplastic left heart syndrome Get access
European Journal of Cardio-Thoracic Surgery, ezaf143, https://doi.org/10.1093/ejcts/ezaf143
Published: 25 April 2025
... hemodynamics congenital heart disease Manuscript including tables Click here to access/download;Manuscript including tables;CORRECT manuscript.docx Aortic arch configurations according to reconstruction methods following the norwood procedure for hypoplastic left heart syndrome Takeaki Harada, MD, PhD...
Journal Article
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Endoscopic submucosal dissection for visible dysplasia in IBD: A nationwide multicenter cohort from the GETAID and the SFED Get access
Journal of Crohn's and Colitis, jjaf057, https://doi.org/10.1093/ecco-jcc/jjaf057
Published: 25 April 2025
... to allow for en-bloc resection with very low recurrence rates and organ sparing in patients without inflammatory bowel disease (IBD). Data on ESD for the management of colorectal dysplasia in IBD patients are scarce. We aimed to evaluate the efficacy and safety of ESD for the treatment of IBD. Methods...
Journal Article
ACCEPTED MANUSCRIPT
“I Can't Let it Stop Me”: Perspectives on Aging from Older Adults with Sickle Cell Disease
Journal of Sickle Cell Disease, yoaf017, https://doi.org/10.1093/jscdis/yoaf017
Published: 25 April 2025
... Phone: (919) 684-0628 17 12 2024 08 02 2025 23 04 2025 07 04 2025 © The Author(s) 2025. Published by Oxford University Press on behalf of the Foundation for Sickle Cell Disease Research. 2025 This is an Open Access article distributed under the terms of the Creative Commons...
