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Keywords: Alzheimer’s disease
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Journal Article
Emily H Ho and others
Archives of Clinical Neuropsychology, acaf035, https://doi.org/10.1093/arclin/acaf035
Published: 14 May 2025
... functioning. The Advancing Reliable Measurement in Alzheimer’s Disease and cognitive Aging study validated the NIHTB across a geographically diverse cognitive aging sample. Participants aged >64 with normal cognition (NC), mild cognitive impairment (MCI), and dementia of the Alzheimer type (DAT) across...
Journal Article
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Leepy Paudel
Published: 13 May 2025
... in any medium, provided the original work is properly cited. 23 03 2025 Corresponding Author Mailing: Leepy Paudel, MBBS, Regenerative and Stem Cell Technologies, Johns Hopkins University, 24688 King's Canyon Sq, Aldie, VA, 20105, USA, Email: [email protected] Alzheimer’s disease Astrocyte...
Journal Article
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Chiara Rickenbach and others
Published: 05 May 2025
... RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract The adaptive immune system and neurodegenerative Alzheimer’s disease (AD) are intertwined in multiple ways. Recent studies have reported alterations...
Journal Article
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Douglas Cowman and others
Brain Communications, fcaf169, https://doi.org/10.1093/braincomms/fcaf169
Published: 05 May 2025
..., provided the original work is properly cited. Abstract Stage II preclinical Alzheimer's disease is defined by the presence of increased amyloid-beta evidenced by fluid and/or imaging biomarkers, in the absence of clinical signs and symptoms. Previous research suggests that preclinical sex differences...
Journal Article
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Kellen K Petersen and others
The Journals of Gerontology: Series B, gbaf085, https://doi.org/10.1093/geronb/gbaf085
Published: 02 May 2025
...Kellen K Petersen; Bhargav T Nallapu; Richard B Lipton; Ellen Grober; Christos Davatzikos; Danielle J Harvey; Ilya M Nasrallah; Ali Ezzati; Alzheimer’s Disease Neuroimaging Initiative Address correspondence to: Ali Ezzati, MD. E-mail: [email protected] 10 07 2024 © The Author(s) 2025...
Journal Article
Nha Nguyen and others
Brain Communications, Volume 7, Issue 3, 2025, fcaf159, https://doi.org/10.1093/braincomms/fcaf159
Published: 25 April 2025
...Nha Nguyen; Jesus J Gomar; Jack N Truong; Janos Barbero; Patrick P Do; Andrea Rommal; Alice Oh; David Eidelberg; Jeremy Koppel; An Vo; for the Alzheimer’s Disease Neuroimaging Initiative...
Journal Article
Yongya Kim and others
Journal of Neuropathology & Experimental Neurology, nlaf047, https://doi.org/10.1093/jnen/nlaf047
Published: 24 April 2025
... of Alzheimer disease neuropathological change and Lewy body disease (LBD) using manual and automated immunostaining methods to investigate variability across protocols. We then compared natural log-transformed percent area occupied values (ln%AO) to blinded ordinal severity scores, Braak stages, Thal phases...
Journal Article
Hua Zhong and others
Human Molecular Genetics, ddaf053, https://doi.org/10.1093/hmg/ddaf053
Published: 23 April 2025
... Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Aim: DNA methylation in brain regions represents a potential mechanism linking genetic variation to Alzheimer’s disease (ad) risk, yet most studies have focused on blood-derived methylation markers...
Journal Article
Lianlian Du and others
Brain Communications, Volume 7, Issue 3, 2025, fcaf158, https://doi.org/10.1093/braincomms/fcaf158
Published: 19 April 2025
... Alzheimer’s Disease Research Center): (i) chronological age, (ii) estimated V+ chronicity, (iii) years since baseline scan, and (iv) estimated A+ chronicity. Results indicated that while both diseases are age-related, their onsets and trajectories are independent of each other. In addition, results indicated...
Journal Article
Amedra Basgaran and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf059, https://doi.org/10.1093/braincomms/fcaf059
Published: 15 April 2025
... of all metrics and ensure allocation to groups did not change depending on the year chosen. Heat maps of all three metrics for the year 2017 were then plotted to visualize differences in incidence, prevalence and DALY rates between the countries and regions. Data on the burden of Alzheimer’s disease...
Journal Article
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Zachary G Baker and others
The Journals of Gerontology: Series B, gbaf062, https://doi.org/10.1093/geronb/gbaf062
Published: 12 April 2025
... may reveal unique strengths of Black and Hispanic/Latino networks that could be leveraged to develop care and support for individuals with dementia and those they leave behind. Alzheimer’s Disease and Related Dementias Social Networks Death Bereavement Accepted Manuscript Mapping the Trajectories...
Journal Article
Inês Almeida e Sousa and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf112, https://doi.org/10.1093/braincomms/fcaf112
Published: 10 April 2025
...Inês Almeida e Sousa; Andrew D Grotzinger; Jeremy M Lawrence; Sophie Breunig; Charles R Marshall; Ania Korszun; Isabelle F Foote Both Alzheimer’s disease, the commonest cause of dementia, and schizophrenia are highly heritable traits with an estimated heritability of 71% (for late-onset Alzheimer’s...
Journal Article
Shigeki Yamada and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf122, https://doi.org/10.1093/braincomms/fcaf122
Published: 26 March 2025
... space hydrocephalus, leading to localized brain deformation. Differentiating regional brain volume changes in Hakim’s disease from those in Alzheimer’s disease, Hakim’s disease with Alzheimer’s disease, and mild cognitive impairment provides insights into disease-specific mechanisms. This study aimed...
Journal Article
Raghav Tandon and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf121, https://doi.org/10.1093/braincomms/fcaf121
Published: 25 March 2025
... I Levey; James J Lah; Cassie S Mitchell; Alzheimer’s Disease Neuroimaging Initiative © The Author(s) 2025. Published by Oxford University Press on behalf of the Guarantors of Brain. 2025 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( https...
Journal Article
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Kathi L Heffner and others
Innovation in Aging, igaf033, https://doi.org/10.1093/geroni/igaf033
Published: 22 March 2025
... RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract Background and Objectives The chronic stress of caregiving for a family member with Alzheimer’s disease and related dementias (ADRD) is associated...
Journal Article
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Melody Zuo and others
Published: 22 March 2025
... most prevalent late-onset neurodegenerative disorders, Alzheimer’s disease and Parkinson’s disease. We also discuss lines of evidence from various study designs and methodologies that either support or do not support an association between kidney health and neurodegeneration. We conclude with a summary...
Journal Article
Marcela C Otero and others
The Gerontologist, Volume 65, Issue 5, May 2025, gnaf054, https://doi.org/10.1093/geront/gnaf054
Published: 19 March 2025
... functioning in people living with neurodegenerative diseases and may be a valuable tool for identifying specific socioemotional impairments in the context of neurodegenerative disease. Alzheimer’s disease Caregivers Frontotemporal dementia Informant-reports Measurement development Convergent validity...
Journal Article
Kengo Kawaguchi and others
Age and Ageing, Volume 54, Issue 3, March 2025, afaf058, https://doi.org/10.1093/ageing/afaf058
Published: 18 March 2025
...). The study outcomes were new-onset all-cause dementia and Alzheimer’s disease (AD). To estimate the risk of low BMD on these outcomes, we constructed Cox proportional hazards models that adjusted for covariates (age, care needs, year of cohort entry, comorbidities and medications) using inverse probability...
Journal Article
Yuye Wang and others
Postgraduate Medical Journal, qgaf039, https://doi.org/10.1093/postmj/qgaf039
Published: 17 March 2025
...Yuye Wang; Xiaoqian Niu; Weizhe Zhen; Bin Zhang; Leian Chen; Yuchen Liu; Wei Sun; Dantao Peng Abstract Background Alzheimer’s disease, the most prevalent cause of dementia, is a worldwide health problem. Proteomics is the systematic study of proteins and peptides to provide comprehensive...
Journal Article
Lisa Greutter and others
Neuro-Oncology Advances, Volume 7, Issue 1, January-December 2025, vdaf057, https://doi.org/10.1093/noajnl/vdaf057
Published: 15 March 2025
... With aging populations, the incidence of brain tumors and neurodegenerative diseases is rising. Recently, Alzheimer’s disease neuropathological change (ADNC) has been documented in the tumor-adjacent cortex of 50% of patients with glioblastoma, with isolated hyperphosphorylated tau (pTau) deposits already...