Skip to results
1-20 of 1704
Keywords: Alzheimer’s disease
Sort by
Journal Article
NIH Toolbox Cognition Performance in Older Adults with Normal Cognition, Mild Cognitive Impairment, and Mild Dementia of the Alzheimer’s Type: Results from the ARMADA Study
Get access
Emily H Ho and others
Archives of Clinical Neuropsychology, acaf035, https://doi.org/10.1093/arclin/acaf035
Published: 14 May 2025
... functioning. The Advancing Reliable Measurement in Alzheimer’s Disease and cognitive Aging study validated the NIHTB across a geographically diverse cognitive aging sample. Participants aged >64 with normal cognition (NC), mild cognitive impairment (MCI), and dementia of the Alzheimer type (DAT) across...
Journal Article
ACCEPTED MANUSCRIPT
Comment on “Changes in iPSC-Astrocyte Morphology Reflect Alzheimer’s Disease Patient Clinical Markers” Open Access
Leepy Paudel
in
Stem Cells
Stem Cells, sxaf030, https://doi.org/10.1093/stmcls/sxaf030
Published: 13 May 2025
... in any medium, provided the original work is properly cited. 23 03 2025 Corresponding Author Mailing: Leepy Paudel, MBBS, Regenerative and Stem Cell Technologies, Johns Hopkins University, 24688 King's Canyon Sq, Aldie, VA, 20105, USA, Email: [email protected] Alzheimer’s disease Astrocyte...
Journal Article
ACCEPTED MANUSCRIPT
Altered T-cell reactivity in the early stages of Alzheimer’s disease Open Access
Chiara Rickenbach and others
in
Brain
Brain, awaf167, https://doi.org/10.1093/brain/awaf167
Published: 05 May 2025
... RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract The adaptive immune system and neurodegenerative Alzheimer’s disease (AD) are intertwined in multiple ways. Recent studies have reported alterations...
Journal Article
ACCEPTED MANUSCRIPT
Sex differences in story recall decline in preclinical Alzheimer’s disease Open Access
Douglas Cowman and others
Brain Communications, fcaf169, https://doi.org/10.1093/braincomms/fcaf169
Published: 05 May 2025
..., provided the original work is properly cited. Abstract Stage II preclinical Alzheimer's disease is defined by the presence of increased amyloid-beta evidenced by fluid and/or imaging biomarkers, in the absence of clinical signs and symptoms. Previous research suggests that preclinical sex differences...
Journal Article
ACCEPTED MANUSCRIPT
Development of Simple Risk Scores for Prediction of Brain β-Amyloid and Tau Status in Older Adults With Mild Cognitive Impairment: A Machine Learning Approach
Get access
Kellen K Petersen and others
The Journals of Gerontology: Series B, gbaf085, https://doi.org/10.1093/geronb/gbaf085
Published: 02 May 2025
...Kellen K Petersen; Bhargav T Nallapu; Richard B Lipton; Ellen Grober; Christos Davatzikos; Danielle J Harvey; Ilya M Nasrallah; Ali Ezzati; Alzheimer’s Disease Neuroimaging Initiative Address correspondence to: Ali Ezzati, MD. E-mail: [email protected] 10 07 2024 © The Author(s) 2025...
Journal Article
An artificial intelligence-derived metabolic network predicts psychosis in Alzheimer’s disease Open Access
Nha Nguyen and others
Brain Communications, Volume 7, Issue 3, 2025, fcaf159, https://doi.org/10.1093/braincomms/fcaf159
Published: 25 April 2025
...Nha Nguyen; Jesus J Gomar; Jack N Truong; Janos Barbero; Patrick P Do; Andrea Rommal; Alice Oh; David Eidelberg; Jeremy Koppel; An Vo; for the Alzheimer’s Disease Neuroimaging Initiative...
Journal Article
Reliability and modeling of digital histological measurements in Alzheimer’s disease neuropathologic change and Lewy body disease Open Access
Yongya Kim and others
Journal of Neuropathology & Experimental Neurology, nlaf047, https://doi.org/10.1093/jnen/nlaf047
Published: 24 April 2025
... of Alzheimer disease neuropathological change and Lewy body disease (LBD) using manual and automated immunostaining methods to investigate variability across protocols. We then compared natural log-transformed percent area occupied values (ln%AO) to blinded ordinal severity scores, Braak stages, Thal phases...
Journal Article
Linking DNA methylation in brain regions to Alzheimer’s disease risk: a Mendelian randomization study
Get access
Hua Zhong and others
Human Molecular Genetics, ddaf053, https://doi.org/10.1093/hmg/ddaf053
Published: 23 April 2025
... Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Aim: DNA methylation in brain regions represents a potential mechanism linking genetic variation to Alzheimer’s disease (ad ) risk, yet most studies have focused on blood-derived methylation markers...
Journal Article
Onset ages of cerebrovascular disease and amyloid and effects on cognition in risk-enriched cohorts Open Access
Lianlian Du and others
Brain Communications, Volume 7, Issue 3, 2025, fcaf158, https://doi.org/10.1093/braincomms/fcaf158
Published: 19 April 2025
... Alzheimer’s Disease Research Center): (i) chronological age, (ii) estimated V+ chronicity, (iii) years since baseline scan, and (iv) estimated A+ chronicity. Results indicated that while both diseases are age-related, their onsets and trajectories are independent of each other. In addition, results indicated...
Journal Article
Machine learning determines the incidence of Alzheimer’s disease based on population gut microbiome profile Open Access
Amedra Basgaran and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf059, https://doi.org/10.1093/braincomms/fcaf059
Published: 15 April 2025
... of all metrics and ensure allocation to groups did not change depending on the year chosen. Heat maps of all three metrics for the year 2017 were then plotted to visualize differences in incidence, prevalence and DALY rates between the countries and regions. Data on the burden of Alzheimer’s disease...
Journal Article
ACCEPTED MANUSCRIPT
Mapping the Trajectories of Social Relations for White, Black, and Hispanic/Latino Individuals Approaching Death with Dementia
Get access
Zachary G Baker and others
The Journals of Gerontology: Series B, gbaf062, https://doi.org/10.1093/geronb/gbaf062
Published: 12 April 2025
... may reveal unique strengths of Black and Hispanic/Latino networks that could be leveraged to develop care and support for individuals with dementia and those they leave behind. Alzheimer’s Disease and Related Dementias Social Networks Death Bereavement Accepted Manuscript Mapping the Trajectories...
Journal Article
Examining the genetic relationship between Alzheimer’s disease, schizophrenia and their shared risk factors using genomic structural equation modelling Open Access
Inês Almeida e Sousa and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf112, https://doi.org/10.1093/braincomms/fcaf112
Published: 10 April 2025
...Inês Almeida e Sousa; Andrew D Grotzinger; Jeremy M Lawrence; Sophie Breunig; Charles R Marshall; Ania Korszun; Isabelle F Foote Both Alzheimer’s disease, the commonest cause of dementia, and schizophrenia are highly heritable traits with an estimated heritability of 71% (for late-onset Alzheimer’s...
Journal Article
Regional brain volume changes in Hakim’s disease versus Alzheimer’s and mild cognitive impairment Open Access
Shigeki Yamada and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf122, https://doi.org/10.1093/braincomms/fcaf122
Published: 26 March 2025
... space hydrocephalus, leading to localized brain deformation. Differentiating regional brain volume changes in Hakim’s disease from those in Alzheimer’s disease, Hakim’s disease with Alzheimer’s disease, and mild cognitive impairment provides insights into disease-specific mechanisms. This study aimed...
Journal Article
Stratifying risk of Alzheimer’s disease in healthy middle-aged individuals with machine learning Open Access
Raghav Tandon and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf121, https://doi.org/10.1093/braincomms/fcaf121
Published: 25 March 2025
... I Levey; James J Lah; Cassie S Mitchell; Alzheimer’s Disease Neuroimaging Initiative © The Author(s) 2025. Published by Oxford University Press on behalf of the Guarantors of Brain. 2025 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( https...
Journal Article
ACCEPTED MANUSCRIPT
Speed of Processing Training for Stress Adaptation in Caregivers of a Family Member with Dementia: A Randomized Controlled Trial Open Access
Kathi L Heffner and others
Innovation in Aging, igaf033, https://doi.org/10.1093/geroni/igaf033
Published: 22 March 2025
... RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract Background and Objectives The chronic stress of caregiving for a family member with Alzheimer’s disease and related dementias (ADRD) is associated...
Journal Article
ACCEPTED MANUSCRIPT
The relationship between kidney health and neurodegenerative diseases Open Access
Melody Zuo and others
in
Brain
Brain, awaf113, https://doi.org/10.1093/brain/awaf113
Published: 22 March 2025
... most prevalent late-onset neurodegenerative disorders, Alzheimer’s disease and Parkinson’s disease. We also discuss lines of evidence from various study designs and methodologies that either support or do not support an association between kidney health and neurodegeneration. We conclude with a summary...
Journal Article
Caregiver Assessment of Socioemotional Functioning in People Living With Neurodegenerative Disease (Part 1): Construct Validity of a New Measure Open Access
Marcela C Otero and others
The Gerontologist, Volume 65, Issue 5, May 2025, gnaf054, https://doi.org/10.1093/geront/gnaf054
Published: 19 March 2025
... functioning in people living with neurodegenerative diseases and may be a valuable tool for identifying specific socioemotional impairments in the context of neurodegenerative disease. Alzheimer’s disease Caregivers Frontotemporal dementia Informant-reports Measurement development Convergent validity...
Journal Article
Association of low bone mineral density and dementia in older women: insights from the Longevity Improvement and Fair Evidence Study
Get access
Kengo Kawaguchi and others
Age and Ageing, Volume 54, Issue 3, March 2025, afaf058, https://doi.org/10.1093/ageing/afaf058
Published: 18 March 2025
...). The study outcomes were new-onset all-cause dementia and Alzheimer’s disease (AD). To estimate the risk of low BMD on these outcomes, we constructed Cox proportional hazards models that adjusted for covariates (age, care needs, year of cohort entry, comorbidities and medications) using inverse probability...
Journal Article
Blood biomarkers of Alzheimer’s disease: findings from proteomics
Get access
Yuye Wang and others
Postgraduate Medical Journal, qgaf039, https://doi.org/10.1093/postmj/qgaf039
Published: 17 March 2025
...Yuye Wang; Xiaoqian Niu; Weizhe Zhen; Bin Zhang; Leian Chen; Yuchen Liu; Wei Sun; Dantao Peng Abstract Background Alzheimer’s disease, the most prevalent cause of dementia, is a worldwide health problem. Proteomics is the systematic study of proteins and peptides to provide comprehensive...
Journal Article
Alzheimer’s disease neuropathological change in younger individuals with IDH-mutant glioma Open Access
Lisa Greutter and others
Neuro-Oncology Advances, Volume 7, Issue 1, January-December 2025, vdaf057, https://doi.org/10.1093/noajnl/vdaf057
Published: 15 March 2025
... With aging populations, the incidence of brain tumors and neurodegenerative diseases is rising. Recently, Alzheimer’s disease neuropathological change (ADNC) has been documented in the tumor-adjacent cortex of 50% of patients with glioblastoma, with isolated hyperphosphorylated tau (pTau) deposits already...
Advertisement
Advertisement