Abstract

The metabolic behaviour of uranium in rats has been investigated after the inhalation of uranium ore concentrates. UO3, UF4 and UO2. Subsequently the fate of uranium in workers was assessed by combining the rates of translocation to blood found in animal experiments with mechanical clearance rates determined from human volunteers who had inhaled fused clay particles. Using the methodology, recommendations have been made for the limits on intake of the various uranium compounds studied and also on the value of chest monitoring and urinary excretion measurements for assessing intakes.

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