Abstract

Between 1980 and 1985 eight patients who had splenectomy of were hyposplenic were admitted to University Hospital, Nottingham with pyrexia and bacteraemia. Three of these patients died from fulminant sepsis, and one patient who had meaningitis was left with serious neurological sequelae. All eight patients had had splenectony or splenic irradiation for haematological disease. Str. pneumoniae was the commonest infecting organism. There were 1579 other bacteraemic episodes seen at University Hospital, Nottingham during the same period.

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