https://orcid.org/0000-0001-8196-7800
-
Views
-
Cite
Cite
Y -C Tsai, Y -S Yang, Disseminated cryptococcosis, QJM: An International Journal of Medicine, Volume 117, Issue 11, November 2024, Pages 797–798, https://doi.org/10.1093/qjmed/hcae126
Close - Share Icon Share
Extract
Clinical picture
A 71-year-old female gardener presented with a deteriorating wound on her right index finger caused by wood splinter puncture two weeks prior to admission. A progressively enlarging lump on the right sternoclavicular region was noticed one week after the injury (Figure 1A). She reported unexplained weight loss about 10 kg and poorly controlled blood sugar. Imaging studies including CT scans of the chest and abdomen, as well as a whole body bone scan, identified a left psoas abscess (Figure 1B) and multiple osteolytic lesions on various skeletal sites (Figure 1C).
...
Histological examination following debridement of the finger wound revealed the presence of Cryptococcus neoformans (Figure 1D). Subsequent biopsies of the chest lump and psoas abscess both confirmed cryptococcal infections. Disseminated cryptococcosis was then confirmed. For allergy to liposomal amphotericin B, treatment was initiated with fluconazole and flucytosine. Clinical response was good, and one month after admission, the patient experienced gradual resolution of psoas abscess and healing of the finger wound.
