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Magdalena M. Julkowska, Pinstatic Acid as a Dissection Tool-Kit for Transcriptional and Nontranscriptional Auxin Responses, Plant Physiology, Volume 180, Issue 2, June 2019, Page 708, https://doi.org/10.1104/pp.19.00464
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Auxin is one of the most-studied plant hormones, and it comes in various forms. Whereas indole 3-acetic acid (IAA) is the most biologically active among the endogenous auxins, phenylacetic acid (PAA) is the more abundant auxin form across plant species and organs (Sugawara et al., 2015). IAA and PAA affect the expression of the same set of auxin-responsive genes (Sugawara et al., 2015), but PAA is not transported through the PIN proteins, which are responsible for IAA relocation. Interestingly, PAA does influence the rate of IAA transport (Johnson and Morris, 1987; Simon and Petrá¡ek, 2011), possibly by affecting PIN trafficking in a more direct way. Due to the low mobility of PAA, local control of PAA metabolism might be the sole regulatory mechanism determining PAA levels (Cook, 2019). While we know that PAA is the only phenyl derivative of endogenous auxins, the metabolic pathway for making and breaking PAA remains elusive (Cook et al., 2016).