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Sayoko Mihara, Eiji Hase, Studies on the vegetative life cycle of Chlamydomonas reinhardi Dangeard in synchronous culture V. The transition point for the effect of 6-methyl purine in the cell cycle, Plant and Cell Physiology, Volume 19, Issue 1, February 1978, Pages 83–89, https://doi.org/10.1093/oxfordjournals.pcp.a075582
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Abstract
By following the nuclear division, chloroplast division, cytokinesis and zoospore liberation of Chlamydomonas reinhardi cells exposed to a high concentration of 6-methyl purine (6-MP), corroborative evidence was obtained for our previous conclusion that 6-MP-exposed cells are brought to the starting point of a new round of the cell cycle with abortion of the cycle in process (“return-to-start” effect). This effect did not occur after cells had passed a critical stage (transition point) which seemed to be situated shortly prior to the onset of nuclear division under the conditions used. When 6-MP was applied to cells after the transition point, it caused an advancing effect on their zoospore liberation. A cycloheximide (CHI)-inhibition step existed shortly alter the transition point for 6-MP. A model was proposed for the effects of 6-MP and CHI.