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Deepti Raj, Sahithi Rao Mallyala, Avinash Chirumamilla, Jay Gajjar, Sneh Patel, Anushka Dekhne, Hardik Dineshbhai Desai, 2595. Burden of Lower Respiratory Tract Infection in United States of America and its Trend from 1990-2019: A Benchmarking Analysis from the Global Burden of Disease Study, Open Forum Infectious Diseases, Volume 10, Issue Supplement_2, December 2023, ofad500.2210, https://doi.org/10.1093/ofid/ofad500.2210
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Abstract
Lower respiratory infections (LRIs) cause substantial mortality and morbidity in the United states of America (USA) accounting for 2.78% of all causes of deaths. However, there is a large statewide variation within the United States with regard to LRIs burden. Comparable and consistent state-level measures of total LRIs burden have not been produced previously.
We used Global Burden of Disease Methodology to estimate the burden of LRIs by Age-groups, year, sex, location across the USA.
In 2019, there were 299,564(95% UI 281,732–317,390) prevalent cases of LRIs in the USA, with an age-standardized rate (ASR) of 85.2 (95% UI 78.8-91.9) per 100,000 population. The annual percentage change of total number incidence increased by 14% followed by deaths increased 13% from 1990-2019. Furthermore, Mississippi [20.49 (95% UI 17.4–23.9)] per 100,000 and Tennessee [19.1 (95% UI 16–22.5)]per 100,000 had the highest age-standardized mortality rate (ASMR) in 2019. In 2019, the incidence and DALY were highest in the 60-64 age group,75-79 age group respectively in both females and males.
A) All age-counts, Incidence, Death, DALY B) Age-standardized rate Incidence, Death, DALY
LRIs continue to be a significant burden on the healthcare system in the United States, causing a significant economic impact and affecting vulnerable populations disproportionately. Preventive measures and prompt treatment can help reduce this burden and improve the overall health of the population.
All Authors: No reported disclosures
Author notes
Session: 242. Respiratory Infections - Bacterial
Saturday, October 14, 2023: 12:15 PM
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