
Contents
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Three Stories of Contraceptive Risk Three Stories of Contraceptive Risk
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Depo-Provera’s Domestic Odyssey Depo-Provera’s Domestic Odyssey
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Risk Management Failures Risk Management Failures
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The Food and Drug Administration The Food and Drug Administration
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The Upjohn Company and Pfizer, Inc. The Upjohn Company and Pfizer, Inc.
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Physicians Physicians
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Courts Courts
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A New Risk Management Agenda A New Risk Management Agenda
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A Duty to Act A Duty to Act
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Conclusion: Contraceptive Drug Risk Failure, Human Dignity, and a Duty to Act
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Published:May 2017
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Extract
The odyssey of Depo-Provera has been told as three stories of the politics of contraceptive drug risk management. The stories have joined the national struggle over Upjohn’s FDA application to have the drug licensed as a female contraceptive to the state medical malpractice and products liability issues raised by its contraceptive use and the criminal justice issues raised by its use as a probation and parole condition for sex offenders.
Three Stories of Contraceptive Risk
The three stories of this odyssey have been told by Judith Weisz, Anne MacMurdo, and Roger Gauntlett, whose personal encounters with Depo-Provera joined the national controversy to its state civil and criminal experience. At the center of each story has been a trial in which each played a central role: Judith Weisz chaired the FDA’s Public Board of Inquiry, a science court; Anne MacMurdo was the plaintiff in a state products liability suit against The Upjohn Company; and Roger Gauntlett was the defendant in a state statutory rape trial. Their personal encounters with Depo-Provera involved a wider audience: FDA officials who have critiqued it as an experimental drug, women who have used it as a contraceptive, and men who have been ordered to take it as a criminal sanction.
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