Volume 16, Issue suppl_3, July 2014
Abstracts from the 20th International Conference on Brain Tumor Research and Therapy, July 20-22, 2014, Lake Tahoe, California
Prelims
Course-Program
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page NP, https://doi.org/10.1093/neuonc/nou204
List-of-Sponsors
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page NP, https://doi.org/10.1093/neuonc/nou205
Abstracts
Monday, July 21, 2014
TEMPORAL AND SPACIAL EVOLUTION OF CLONES IN 400 LOW GRADE GLIOMAS IN JAPAN
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii1, https://doi.org/10.1093/neuonc/nou206.1
GENETIC CHANGES IN RADIATION-ASSOCIATED MENINGIOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii1, https://doi.org/10.1093/neuonc/nou206.2
CDKN2A LOSS IS ASSOCIATED WITH SHORTENED SURVIVAL IN INFILTRATING ASTROCYTOMAS BUT NOT OLIGODENDROGLIOMAS OR MIXED OLIGOASTROCYTOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii1–iii22, https://doi.org/10.1093/neuonc/nou206.22
MUTATION-BASED MOLECULAR GLIOMA CLASSIFICATION: PREVALENCE AND ASSOCIATION WITH GERMLINE RISK SNPS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii1, https://doi.org/10.1093/neuonc/nou206.3
IMAGING BIOMARKERS OF MALIGNANT PROGRESSION OF DIFFUSE LOW-GRADE GLOMA (LGG)
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii1–iii22, https://doi.org/10.1093/neuonc/nou206.43
PROCOAGULANT TISSUE FACTOR EXPRESSION IS LINKED TO DISTINCT SUBTYPES IN GLIOBLASTOMA AND PLAYS A ROLE IN TUMOR DORMANCY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii1–iii22, https://doi.org/10.1093/neuonc/nou206.77
IMAGE GUIDED RNA-SEQ REVEALS SUBTYPE-SPECIFIC PATTERNS AT THE INFILTRATIVE MARGINS OF GLIOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii10, https://doi.org/10.1093/neuonc/nou206.34
ANNEXIN A2 REGULATES ANGIOGENESIS AND INVASION PHENOTYPES OF MALIGNANT GLIOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii10, https://doi.org/10.1093/neuonc/nou206.35
INTRAOPERATIVE CONTRAST ENHANCED ULTRASOUND IN BRAIN TUMOR SURGERY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii10, https://doi.org/10.1093/neuonc/nou206.36
NOVEL ALKYLPHOSPHOCHOLINE ANALOGS FOR BROAD SPECTRUM CANCER IMAGING AND THERAPY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii10–iii11, https://doi.org/10.1093/neuonc/nou206.37
INFORMATION-GUIDED SURGERY USING INTRAOPERATIVE MRI AND FUNCTIONAL MAPPING FOR GLIOMAS.
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii11, https://doi.org/10.1093/neuonc/nou206.38
IN SITU METABOLIC PROFILING SHEDS LIGHT ON OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT OLIGODENDROGLIOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii11, https://doi.org/10.1093/neuonc/nou206.39
IMMUNE CHECKPOINT BLOCKADE FOR GLIOBLASTOMA: PRECLINICAL ACTIVITY OF SINGLE AGENT AND COMBINATORIAL THERAPY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii11–iii12, https://doi.org/10.1093/neuonc/nou206.40
METABOLIC IMAGING BIOMARKERS FOR MUTANT IDH1 GLIOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii12, https://doi.org/10.1093/neuonc/nou206.41
INCREASED PERFUSION DUE TO VASCULAR NORMALIZATION IMPROVES OXYGENATION AND SURVIVAL IN GLIOBLASTOMA PATIENTS TREATED WITH CEDIRANIB WITH OR WITHOUT CHEMORADIATION
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii12, https://doi.org/10.1093/neuonc/nou206.42
EX VIVO METABOLIC SIGNATURES OF GLIOMAS BASED UPON TUMOR GRADE, IMAGING CHARACTERISTICS AND TREATMENT HISTORY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii12–iii13, https://doi.org/10.1093/neuonc/nou206.44
PROGNOSTIC VALUE OF O-(2-[18F]FLUORETHYL)-L-TYROSINE POSITRON EMISSION TOMOGRAPHY (18FET-PET) WITHIN THE CLINICAL COURSE IN NEWLY DIAGNOSED GLIOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii13, https://doi.org/10.1093/neuonc/nou206.45
A PHASE I STUDY OF CONVECTION-ENHANCED DELIVERY OF LIPOSOMAL-IRINOTECAN USING REAL-TIME IMAGING WITH GADOLINIUM IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii13, https://doi.org/10.1093/neuonc/nou206.46
PREOPERATIVE DYNAMIC CONTRAST-ENHANCED MRI CORRELATES WITH MOLECULAR MARKERS OF HYPOXIA AND VASCULARITY IN SPECIFIC AREAS OF INTRATUMORAL MICROENVIRONMENT AND IS PREDICTIVE OF PATIENT OUTCOME
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii13, https://doi.org/10.1093/neuonc/nou206.47
REAL-TIME ATLAS-BASED STEREOTACTIC NEURONAVIGATION
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii14, https://doi.org/10.1093/neuonc/nou206.48
BRAIN TUMOR SURGERY NAVIGATION SYSTEM BASED ON UPDATING PREOPERATIVE IMAGES USING POSITIONAL INFORMATION OF SURGICAL TOOLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii14, https://doi.org/10.1093/neuonc/nou206.49
GLIOBLASTOMA STEM CELL-DERIVED PERICYTES AND TUMOR ANGIOGENESIS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii14, https://doi.org/10.1093/neuonc/nou206.50
SINGLE CELL DERIVED CLONAL ANALYSIS OF HUMAN GLIOBLASTOMA LINKS FUNCTIONAL AND GENOMIC HETEROGENEITY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii14, https://doi.org/10.1093/neuonc/nou206.51
MUTANT EGFR SUPPRESSION OF MICRORNA-9 INDUCES FOXP1 TO ENHANCE GLIOBLASTOMA TUMORIGENICITY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii14–iii15, https://doi.org/10.1093/neuonc/nou206.52
PRESENCE OF A DISTINCTIVE MYELOID POPULATION IS ASSOCIATED WITH THE INVASIVE TUMOR PHENOTYPE OBSERVED AFTER ANTI-ANGIOGENESIS THERAPIES
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii15, https://doi.org/10.1093/neuonc/nou206.53
EPIGENETIC REGULATION OF GBM CELL STEMNESS AND TUMOR PROPAGATING CAPACITY BY OCT4 AND SOX2
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii15, https://doi.org/10.1093/neuonc/nou206.54
MOVING BEYOND VEGF: INHIBING GLIOMA ANGIOGENESIS BY TARGETING THE TIE2/ANGIOPOIETIN SIGNALING PATHWAY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii15, https://doi.org/10.1093/neuonc/nou206.55
TARGET IDENTIFICATION IN GLIOMA INITIATING CELLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii15–iii16, https://doi.org/10.1093/neuonc/nou206.56
C11ORF95-RELA FUSIONS DRIVE ONCOGENIC NF-KB SIGNALING IN EPENDYMOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii16, https://doi.org/10.1093/neuonc/nou206.57
EPIGENOME ALTERATIONS DEFINE LETHAL CIMP POSITIVE EPENDYMOMAS OF INFANCY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii16, https://doi.org/10.1093/neuonc/nou206.58
UNDERSTANDING AND TACKLING THE TUMOR-IMMUNE CELL DIALOGUE DURING PROGRESSION AND THERAPEUTIC RESISTANCE
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii16, https://doi.org/10.1093/neuonc/nou206.59
EGFR PHOSPHORYLATION OF DCBLD2 RECRUITS TRAF6 AND STIMULATES AKT-PROMOTED TUMORIGENESIS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii16–iii17, https://doi.org/10.1093/neuonc/nou206.60
DEVELOPMENT OF NOVEL SMALL MOLECULES THAT TARGET GLIOBLASTOMA STEM CELLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii17, https://doi.org/10.1093/neuonc/nou206.61
INTEGRATION OF CANCER STEM CELL MAINTENANCE AND LIPID METABOLISM BY SCAVENGER RECEPTORS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii17, https://doi.org/10.1093/neuonc/nou206.62
DISTINCT AND SEPARABLE ROLES FOR HISTONE METHYLTRANSFERASE EZH2 IN NEUROGENIC ASTROCYTES
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii17, https://doi.org/10.1093/neuonc/nou206.63
A NOVEL POLYCOMB FEED FORWARD LOOP IN GLIOBLASTOMA MULTIFORME
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii17, https://doi.org/10.1093/neuonc/nou206.64
EXTRACELLULAR REGULATORS OF GLIOBLASTOMA SIGNALING
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii18, https://doi.org/10.1093/neuonc/nou206.65
MOLECULAR MOTORS AS NOVEL TARGETS TO BLOCK GLIOMA DISPERSION AND PROLIFERATION
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii18, https://doi.org/10.1093/neuonc/nou206.66
CELL INTRINSIC SEXUAL DIMORPHISM IN THE RB AND P21 PATHWAYS UNDERLIES MALE PREDOMINANCE IN GBM
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii18–iii19, https://doi.org/10.1093/neuonc/nou206.67
INTEGRATED ANALYSIS IDENTIFIES DIFFERENT METABOLIC SIGNATURES WITHIN BOTH TUMOR-INITIATING CELLS AND STEM CELLS IN A MURINE GLIOBLASTOMA MODEL
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii19, https://doi.org/10.1093/neuonc/nou206.68
GLIOMA STEM CELL HOMING TO THE HUMAN SUBVENTRICULAR ZONE
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii19, https://doi.org/10.1093/neuonc/nou206.69
A NOVEL P53 BYSTANDER EFFECT INDUCES GLIOBLASTOMA CELL DEATH THROUGH A GLYCOSYLATION-DEPENDENT MECHANISM
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii19, https://doi.org/10.1093/neuonc/nou206.70
ABERRANT SPLICING OF A BRAIN-ENRICHED ALTERNATIVE EXON ELIMINATES TUMOR SUPPRESSOR FUNCTION AND PROMOTES ONCOGENE FUNCTION DURING BRAIN TUMORIGENESIS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii19–iii20, https://doi.org/10.1093/neuonc/nou206.71
TELOMERE LENGTH VARIANTS ARE ASSOCIATED WITH HIGH-GRADE GLIOMA RISK: IDENTIFICATION OF A NOVEL GLIOMA RISK LOCUS BY GENOME-WIDE ASSOCIATION STUDY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii2, https://doi.org/10.1093/neuonc/nou206.4
TREE DERIVED SURVIVAL RISK GROUPS IN DIFFERENTIATING RISK FOR GLIOMA PATIENTS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii2, https://doi.org/10.1093/neuonc/nou206.5
A NEW CLINICAL GUIDELINE (2007) AND NATIONAL AWARENESS CAMPAIGN (2011) ACCELERATED BRAIN TUMOUR DIAGNOSIS IN UK CHILDREN (HEADSMART - BE BRAIN TUMOUR AWARE)
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii2, https://doi.org/10.1093/neuonc/nou206.6
SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) ASSOCIATED WITH GLIOMA SURVIVAL
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii2, https://doi.org/10.1093/neuonc/nou206.7
COMBINED DRUG SCREENING AND PHOSPHOPROTEOMICS IDENTIFIES CANDIDATE BRAIN TUMOR THERAPEUTICS AND NOVEL TARGETS IN PRIMARY HUMAN BRAIN TUMOR-INITIATING CELLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii20, https://doi.org/10.1093/neuonc/nou206.72
THE WARBURG EFFECT AND BEYOND
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii20, https://doi.org/10.1093/neuonc/nou206.73
HUR DEPENDENT REGULATION OF CENTROSOMES
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii20, https://doi.org/10.1093/neuonc/nou206.74
EPIGENETICALLY DISTURBED NEURAL STEM/PROGENITOR CELLS IN THE PRE-NEOPLASTIC STAGE OF PDGF-INDUCED MOUSE GLIOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii20–iii21, https://doi.org/10.1093/neuonc/nou206.75
STEM- AND PROGENITOR-LIKE CELL CONTRIBUTION TO MALIGNANT ASTROCYTOMA HETEROGENEITY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii21, https://doi.org/10.1093/neuonc/nou206.76
MECHANISMS OF ADAPTIVE RADIOPROTECTION IN GLIOMA STEM CELLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii21, https://doi.org/10.1093/neuonc/nou206.78
INHIBITING INVASION AND STEMNESS IN GLIOBLASTOMA BY THYMOSIN BETA 4 GENE SILENCING: A POTENTIAL THERAPEUTIC TARGET?
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii21–iii22, https://doi.org/10.1093/neuonc/nou206.79
FUNCTION OF ECOTROPIC VIRAL INTEGRATION SITE 1 (EVI1) GENE IN MOUSE NEURAL PRECURSOR CELLS AND HUMAN GLIOMA INITIATING CELLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii22, https://doi.org/10.1093/neuonc/nou206.80
Tuesday, July 22, 2014
PHASE I INDIVIDUAL DOSE TITRATION TRIAL OF THE HUMAN CORTICOTROPIN-RELEASING FACTOR (HCRF), CORTICORELIN ACETATE INJECTION (XERECEPT) IN PEDIATRIC PATIENTS WITH PERITUMORAL EDEMA OF THE BRAIN
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii23, https://doi.org/10.1093/neuonc/nou208.1
WHOLE EXOME SEQUENCING IDENTIFIED THAT THE MAPK AND PI3K PATHWAYS ARE THE MAIN TARGETS FOR MUTATIONS IN INTRACRANIAL GERM CELL TUMORS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii23, https://doi.org/10.1093/neuonc/nou208.2
MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii23, https://doi.org/10.1093/neuonc/nou208.3
STRUCTURAL VARIANTS SHUFFLE CHROMATIN TO ACTIVATE GFI1 FAMILY ONCOGENES IN MEDULLOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii24, https://doi.org/10.1093/neuonc/nou208.4
ASSESSING THE UTILITY OF CLINICAL TUMOR SEQUENCING IN THE PEDIATRIC NEURO-ONCOLOGY CLINIC
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii24, https://doi.org/10.1093/neuonc/nou208.5
INFORMING TREATMENT DECISIONS IN RELAPSED PEDIATRIC MALIGNANCIES USING NEXT-GENERATION DIAGNOSTICS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii24, https://doi.org/10.1093/neuonc/nou208.6
PROGNOSTIC SIGNIFICANCE OF CLINICAL, HISTOPATHOLOGICAL, AND MOLECULAR CHARACTERISTICS OF MEDULLOBLASTOMAS IN THE PROSPECTIVE HIT2000 MULTICENTER CLINICAL TRIAL COHORT
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii24–iii25, https://doi.org/10.1093/neuonc/nou208.7
TRANSCRIPTIONAL REGULATION OF OLIGODENDROGLIAL CELL FATE BY DLX HOMEOBOX GENES: POTENTIAL RELEVANCE TO HISTONE H3.3 MUTATIONS IN PEDIATRIC HIGH GRADE GLIOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii25, https://doi.org/10.1093/neuonc/nou208.10
ABCG2 AND MDR PROMOTE BRAINSTEM GLIOMAGENESIS AND LIMIT THE EFFICACY OF DASATINIB IN A DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) MOUSE MODEL
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii25, https://doi.org/10.1093/neuonc/nou208.8
EPIGENETIC TARGETING OF HEDGEHOG PATHWAY TRANSCRIPTIONAL OUTPUT
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii25, https://doi.org/10.1093/neuonc/nou208.9
PID1 IS A NOVEL SENSITIZER OF BRAIN TUMOR CELLS TO CHEMOTHERAPY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii26, https://doi.org/10.1093/neuonc/nou208.11
PRELIMINARY RESULTS OF A PROSPECTIVE FEASIBILITY PILOT STUDY OF “GEMPOX” (GEMCITABINE, OXALIPLATIN, AND PACLITAXEL) IN PEDIATRIC AND ADULT PATIENTS WITH REFRACTORY OR RECURRENT CENTRAL NERVOUS SYSTEM (CNS) GERM CELL TUMORS (GCT): THE INTERNATIONAL CNS GCT CONSORTIUM TRIAL, CNS GCT-4
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii26, https://doi.org/10.1093/neuonc/nou208.12
BIOLOGICALLY-BASED THERAPEUTICS FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii26, https://doi.org/10.1093/neuonc/nou208.13
DETAILED MOLECULAR CHARACTERISATION OF DIFFUSE INTRINSIC PONTINE GLIOMAS IDENTIFIES THREE MOLECULAR SUBGROUPS AND A NOVEL CANCER DRIVER, ACVR1
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii26–iii27, https://doi.org/10.1093/neuonc/nou208.14
FINAL RESULTS OF A PROSPECTIVE MULTI-INSTITUTIONAL PHASE II STUDY OF EVEROLIMUS (RAD001), AN MTOR INHIBITOR, IN PEDIATRIC PATIENTS WITH RECURRENT OR PROGRESSIVE LOW-GRADE GLIOMA. A POETIC CONSORTIUM TRIAL
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii27, https://doi.org/10.1093/neuonc/nou208.15
POTENCY OF SECRETING HCG-β IN GERMINOMAS. CLINICAL AND BIOLOGICAL ANALYSIS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii27, https://doi.org/10.1093/neuonc/nou208.16
PROGNOSTIC MARKER ANALYSIS IN PEDIATRIC POSTERIOR FOSSA EPENDYMOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii27, https://doi.org/10.1093/neuonc/nou208.17
TARGETING RESISTANCE PATHWAYS IN BRAF-MUTANT PEDIATRIC GLIOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii27–iii28, https://doi.org/10.1093/neuonc/nou208.18
INTRACRANIAL GERM CELL TUMORS WITH MTOR MUTATION ARE COMMON IN BASAL GANGLIA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii28, https://doi.org/10.1093/neuonc/nou208.19
METASTASIS AND TUMOR RECURRENCE FROM RARE SOX9-POSITIVE CELLS IN MYCN-DRIVEN MEDULLOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii28, https://doi.org/10.1093/neuonc/nou208.20
LONG-TERM OUTCOME OF CENTRALLY LOCATED LOW-GRADE GLIOMA IN CHILDREN
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii28, https://doi.org/10.1093/neuonc/nou208.21
HIGH-THROUGHPUT DRUG SCREENING IDENTIFIES HDAC INHIBITORS AS CANDIDATE THERAPEUTICS FOR MYC-DRIVEN MEDULLOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii29, https://doi.org/10.1093/neuonc/nou208.22
C19MC ONCOMIRS CONVERGE ON MULTIPLE CELL CYCLE REGULATORS TO MODULATE NEURAL DIFFERENTIATION AND THE TUMOR EPIGENOME
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii29, https://doi.org/10.1093/neuonc/nou208.23
HIGHLY SELECTIVE INTRA-ARTERIAL CHEMOTHERAPY FOR THE TREATMENT OF PROGRESSIVE DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPG)
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii29, https://doi.org/10.1093/neuonc/nou208.24
KIAA1549:BRAF FUSION GENE IN PEDIATRIC BRAIN TUMORS OF DIFFERENT HISTOGENESIS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii29, https://doi.org/10.1093/neuonc/nou208.25
HISTOPATHOLOGIC EVALUATION OF H3K27ME3 IS A PROGNOSTIC BIOMARKER FOR PEDIATRIC GLIOBLASTOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii29–iii30, https://doi.org/10.1093/neuonc/nou208.26
Monday, July 21, 2014
THE P53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii3, https://doi.org/10.1093/neuonc/nou206.10
INTEGRATIVE GENOMIC CHARACTERIZATION OF LOWER GRADE GLIOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii3, https://doi.org/10.1093/neuonc/nou206.11
INITIAL SYMPTOMS OF PINEAL REGION TUMORS - COMPARISON TO HISTORICAL CONTROL OF PRE-CT ERA -
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii3, https://doi.org/10.1093/neuonc/nou206.8
INCIDENCE AND OUTCOMES IN GLIOMAS FROM BRAIN TUMOR REGISTRY OF JAPAN 2001-2004
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii3, https://doi.org/10.1093/neuonc/nou206.9
Tuesday, July 22, 2014
CONVECTION-ENHANCED DELIVERY OF NIMUSTINE HYDROCHLORIDE FOR BRAINSTEM MALIGNANT GLIOMA: CURRENT STUDY AND DEVELOPMENT OF NEW DEVICE
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii30, https://doi.org/10.1093/neuonc/nou208.27
QUALITY OF LIFE OF EXTREMELY LONG-TIME SURVIVORS WITH GERMINOMA MAINLY TREATED WITH RADIOTHERAPY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii30, https://doi.org/10.1093/neuonc/nou208.28
THOR METHYLATION PROVIDES INSIGHT INTO THE TELOMERE MAINTENANCE LANDSCAPE OF MALIGNANT GLIOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii30, https://doi.org/10.1093/neuonc/nou208.29
HISTONE DEACETYLASE INHIBITOR PCI-24781 SHOWS ANTIPROLIFERATIVE EFFECTS AGAINST PEDIATRIC GLIOBLASTOMA CELLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii30–iii31, https://doi.org/10.1093/neuonc/nou208.30
MTOR KINASE INHIBITORS AND APOPTOSIS IN GLIOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii31, https://doi.org/10.1093/neuonc/nou208.31
OPTIMIZATION OF DEMETHYLATING THERAPY FOR IDH1 MUTANT GLIOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii31, https://doi.org/10.1093/neuonc/nou208.32
IDENTIFYING DRUG COMPOUNDS TARGETING TUMOR METABOLISM IN GLIOBLASTOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii31, https://doi.org/10.1093/neuonc/nou208.33
A C-MET-ß1 INTEGRIN COMPLEX DRIVES INVASIVE RESISTANCE TO ANTI-ANGIOGENIC THERAPY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii31–iii32, https://doi.org/10.1093/neuonc/nou208.34
MAPPING THE GLIOBLASTOMA METABOLOME AFTER BEVACIZUMAB THERAPY BY 13C6-GLUCOSE METABOLOMIC FLUX ANALYSIS.
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii32, https://doi.org/10.1093/neuonc/nou208.35
HIGH-THROUGHPUT SCREENING OF GLIOMA STEM CELL LINES FOR DRUG STRUCTURE- AND GENOTYPE-CORRELATED SENSITIVITY TO A PANEL OF TYROSINE KINASE INHIBITORS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii32, https://doi.org/10.1093/neuonc/nou208.36
HIGH INTERSTITIAL FLUID PRESSURE REGULATES TUMOR GROWTH AND DRUG UPTAKE IN HUMAN GLIOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii32, https://doi.org/10.1093/neuonc/nou208.37
MUTANT IDH1-DRIVEN CELLULAR TRANSFORMATION INCREASES RAD51-MEDIATED HOMOLOGOUS RECOMBINATION AND TEMOZOLOMIDE (TMZ) RESISTANCE.
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii33, https://doi.org/10.1093/neuonc/nou208.38
AN ALL HUMAN 3D IN VITRO MODEL OF THE BLOOD BRAIN BARRIER IN NANOPARTICLE DELIVERY AND CANCER METASTASIS STUDIES
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii33, https://doi.org/10.1093/neuonc/nou208.39
INFLUENCE OF DRUG DELIVERY ON THERAPEUTIC BENEFIT IN GBM–CDK4 AND MDM2 INHIBITOR COMPARISON IN FLANK VERSUS ORTHOTOPIC MODELS AND COMPARISON OF BRAIN PENETRANT VERSUS IMPENETRANT PI3K/MTOR INHIBITORS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii33, https://doi.org/10.1093/neuonc/nou208.40
RB1 SUPPRESSION IS RESPONSIBLE FOR ACQUIRED CDK4/6 INHIBITOR RESISTANCE IN GLIOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii33–iii34, https://doi.org/10.1093/neuonc/nou208.41
EPHRINA2 RECEPTOR IN HUMAN GLIOBLASTOMA CANCER STEM CELLS AND IDENTIFICATION OF NEW, PUTATIVE THERAPEUTIC TARGETS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii34, https://doi.org/10.1093/neuonc/nou208.42
TRANSCRIPTIONAL PROFILING OF GBM INVASIVE GENES IDENTIFIES EFFECTIVE INHIBITORS OF THE LIM KINASE-COFILIN PATHWAY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii34, https://doi.org/10.1093/neuonc/nou208.43
CONTEXT OF VULNERABILITY OF GBM: DESCRIPTIVE GENOMICS LEADING TO EMPIRIC THERAPEUTICS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii34–iii35, https://doi.org/10.1093/neuonc/nou208.44
IDENTIFICATION AND PRELIMINARY TREATMENT DATA OF XENOGRAFTS REPRESENTING TCGA-DEFINED SUBTYPES
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii35, https://doi.org/10.1093/neuonc/nou208.45
BRAIN TUMOUR INITIATING CELLS AND TARGETING STAT3 ONCOGENIC SIGNALLING IN GBM
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii35, https://doi.org/10.1093/neuonc/nou208.46
FORETINIB IS EFFECTIVE THERAPY FOR METASTATIC SONIC HEDGEHOG MEDULLOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii35, https://doi.org/10.1093/neuonc/nou208.47
NEO212: A NOVEL TEMOZOLOMIDE-PERILLYL ALCOHOL CONJUGATE EXHIBITS SUPERIOR ACTIVITY AGAINST TEMOZOLOMIDE RESISTANT GLIOMAS AND INTRACRANIAL TRIPLE NEGATIVE BREAST CANCER METASTASIS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii35–iii36, https://doi.org/10.1093/neuonc/nou208.48
DIRECT CELL CONTACT BETWEEN BRAIN ENDOTHELIAL CELLS AND GLIOMA STEM CELLS PROMOTES ENDOTHELIAL CELL MIGRATION
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii36, https://doi.org/10.1093/neuonc/nou208.49
EFFECTS OF SIMULATED MICROGRAVITY ON PROLIFERATION AND CHEMOSENSITIVITY IN MALIGNANT GLIOMA CELLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii36, https://doi.org/10.1093/neuonc/nou208.50
MRE11-RAD50-NBS1 COMPLEX INHIBITOR MIRIN ENHANCES RADIOSENSITIVITY IN HUMAN GLIOBLASTOMA CELLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii36, https://doi.org/10.1093/neuonc/nou208.51
GLIOMA SPECIFIC PEPTIDES: A PLATFORM FOR MOLECULAR IMAGING AND THERAPEUTIC TARGETING
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii37, https://doi.org/10.1093/neuonc/nou208.52
DIFFERENT MECHANISMS OF TUMOR GROWTH INHIBITION BY BLOCKADE OF IGF-IR IN U87-INDUCED AND STEM-LIKE CELL-INDUCED GLIOBLASTOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii37, https://doi.org/10.1093/neuonc/nou208.53
TRAIL POTENTIATES PANOBINOSTAT CYTOTOXICITY IN GLIOBLASTOMA MULTIFORME (GBM) IN VITRO
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii37, https://doi.org/10.1093/neuonc/nou208.54
MICRO RNA BASED STRATEGY FOR ENHANCING THE EFFECT OF ONCOLYTIC HSV-1 VIRUS THERAPY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii37, https://doi.org/10.1093/neuonc/nou208.55
DECIPHERING INTRINSIC AND ADAPTIVE RESISTANCE TO PI3K PATHWAY INHIBITORS IN GLIOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii37–iii38, https://doi.org/10.1093/neuonc/nou208.56
PATIENT-DERIVED XENOGRAFTS MIRROR THE PROTEOMIC PROFILE OF HUMAN GLIOBLASTOMA: IMPLICATIONS FOR PERSONALIZED DRUG DEVELOPMENT
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii38, https://doi.org/10.1093/neuonc/nou208.57
CABOZANTINIB IS EFFECTIVE IN A SUBSET OF XENOGRAFT GBM TUMORS AND AFFECTS MULTIPLE SIGNALING PATHWAYS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii38, https://doi.org/10.1093/neuonc/nou208.58
YAP IS A CRITICAL AND NOVEL REGULATOR OF MIGRATION AND INVASION AND PREDICTS POOR OUTCOME IN GLIOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii38–iii39, https://doi.org/10.1093/neuonc/nou208.59
WT1 PEPTIDE VACCINATION FOR MALIGNANT GLIOMAS AS A PART OF MULTI-MODAL THERAPY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii39, https://doi.org/10.1093/neuonc/nou208.60
FIRST-IN-HUMAN PHASE I CLINICAL TRIAL OF ONCOLYTIC DELTA-24-RGD (DNX-2401) WITH BIOLOGICAL ENDPOINTS: IMPLICATIONS FOR VIRO- IMMUNOTHERAPY
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii39, https://doi.org/10.1093/neuonc/nou208.61
ROBUST INDUCTION OF TYPE-1 CD8+ T-CELL RESPONSES IN WHO GRADE II LOW-GRADE GLIOMA PATIENTS RECEIVING PEPTIDE-BASED VACCINES IN COMBINATION WITH POLY-ICLC
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii39, https://doi.org/10.1093/neuonc/nou208.62
RANDOMIZATION OF PATIENTS WITH GLIOBLASTOMA TO VACCINE SITE PRE-CONDITIONING WITH TETANUS-DIPHTHERIA TOXOID SYSTEMICALLY ENHANCES MIGRATION AND THERAPEUTIC EFFECT OF CYTOMEGALOVIRUS PP65-PULSED DENDRITIC CELL VACCINE IN A MIP-1α-DEPENDENT FASHION
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii39–iii40, https://doi.org/10.1093/neuonc/nou208.63
Monday, July 21, 2014
MODELLING HIGH MYC MEDULLOBLASTOMA AND OTHER BRAIN TUMORS USING HUMAN NEURAL STEM CELLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii4, https://doi.org/10.1093/neuonc/nou206.12
NEXT-GENERATION NEUROPATHOLOGY - IMPROVING DIAGNOSTIC ACCURACY FOR BRAIN TUMORS USING DNA METHYLATION ARRAY-BASED MOLECULAR PROFILING
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii4, https://doi.org/10.1093/neuonc/nou206.13
PROGNOSTIC AND PREDICTIVE BIOMARKER-BASED SUBGROUPS IN THE NOA-04 TRIAL
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii4, https://doi.org/10.1093/neuonc/nou206.14
MIF-CD74 GUIDED THERAPEUTIC STRATEGY FOR THE UPFRONT TREATMENT OF GBM PATIENTS WITH AN UNMETHYLATED MGMT PROMOTER
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii4–iii5, https://doi.org/10.1093/neuonc/nou206.15
Tuesday, July 22, 2014
THE IMPACT OF OXYGEN TENSION ON CD8+ T CELL FUNCTION AND INTERACTION WITH GLIOMA CELLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii40, https://doi.org/10.1093/neuonc/nou208.64
IDH1 MUTATIONS AS A IMMUNOTHERAPEUTIC TARGET FOR BRAIN TUMORS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii40, https://doi.org/10.1093/neuonc/nou208.65
FUNCTIONAL PRESENCE OF M2 MACROPHAGE MARKERS IN GBM TUMOR CELLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii40–iii41, https://doi.org/10.1093/neuonc/nou208.66
NEW GLIOMA-ASSOCIATED AUTO-ANTIBODIES
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii41, https://doi.org/10.1093/neuonc/nou208.67
GLIOMAS PROMOTE INDUCTION OF B7-H1/PD-L1 EXPRESSION ON MONOCYTES: CLINICAL EVIDENCE OF AN IMMUNOSUPPRESSIVE MECHANISM THAT CAN BE TARGETED WITH ANTIBODY BLOCKADE
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii41, https://doi.org/10.1093/neuonc/nou208.68
ONCOLYTIC POLIOVIRUS IMMUNOTHERAPY OF GLIOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii41, https://doi.org/10.1093/neuonc/nou208.69
Wednesday, July 23, 2014
SPONTANEOUS IMMUNE RESPONSES IN GBM PATIENTS AFTER COMPLETE TUMOR RESECTION ARE ASSOCIATED WITH AN IMPROVED SURVIVAL
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii42, https://doi.org/10.1093/neuonc/nou209.1
VSTAT120 REDUCES THE INNATE INFLAMMATORY RESPONSE TO INFECTION AND ENHANCES ONCOLYTIC VIRAL THERAPY FOR GLIOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii42, https://doi.org/10.1093/neuonc/nou209.2
NK CELLS FROM GLIOMA-BEARING MICE TREATED WITH TEMOZOLOMIDE ARE ENRICHED FOR GENES RELATED TO MULTI-DRUG RESISTANCE AND CHEMOTAXIS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii42–iii52, https://doi.org/10.1093/neuonc/nou209.3
EFFECT OF TEMOZOMIDE ON HUMAN DENDRITIC CELLS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii42–iii43, https://doi.org/10.1093/neuonc/nou209.4
ONCOLYTIC POLIO/RHINOVIRUS RECOMBINANT (PVSRIPO) IN RECURRENT GLIOBLASTOMA (GBM): FIRST PHASE I CLINICAL TRIAL EVALUATING THE INTRATUMORAL ADMINISTRATION
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii43, https://doi.org/10.1093/neuonc/nou209.5
NEXT-GENERATION RECOMBINANT IMMUNOTOXINS FOR GLIOBLASTOMAS AND MELANOMAS TREATMENT
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii43, https://doi.org/10.1093/neuonc/nou209.6
GENOME-WIDE ANALYSIS UNCOVERS RECURRENT ALTERATIONS IN PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMAS (PCNSL)
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii43, https://doi.org/10.1093/neuonc/nou209.7
THE ROLE OF MYELOID DERIVED SUPPRESSOR CELLS (MDSCS) IN TUMOR-INDUCED IMMUNOSUPPRESSION IN HUMAN AND MURINE GLIOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii44, https://doi.org/10.1093/neuonc/nou209.10
BENEFICIAL OUTCOMES AFTER PCV PLUS RT IN OLIGODENDROGLIAL TUMORS ARE ASSOCIATED WITH DETECTION OR RISK OF AN IDH MUTATION
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii44–iii45, https://doi.org/10.1093/neuonc/nou209.11
LOSS OF SPARC IN P53-NULL ASTROCYTES PROMOTES MACROPHAGE ACTIVATION AND PHAGOCYTOSIS RESULTING IN DECREASED TUMOR SIZE AND TUMOR CELL SURVIVAL
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii44, https://doi.org/10.1093/neuonc/nou209.8
ERBB2/HER2-SPECIFIC NATURAL KILLER CELLS FOR ADOPTIVE IMMUNOTHERAPY OF GLIOBLASTOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii44, https://doi.org/10.1093/neuonc/nou209.9
TERT PROMOTER MUTATIONS CONTRIBUTE TO PROGNOSTIC SUBGROUPS OF LOWER GRADE ASTROCYTOMAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii45, https://doi.org/10.1093/neuonc/nou209.12
PRE-OPERATIVE CHEMOTHERAPY AS A NEW STRATEGY OF TREATMENT FOR LOW GRADE GLIOMAS IN ELOQUENT AREAS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii45, https://doi.org/10.1093/neuonc/nou209.13
ELUCIDATING THE ONCOGENIC ROLE OF ATRX DEFICIENCY IN GLIOMA
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii45, https://doi.org/10.1093/neuonc/nou209.14
EVOLUTION OF THE GLIOBLASTOMA GENOME IN RESPONSE TO TREATMENTS
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Pages iii45–iii46, https://doi.org/10.1093/neuonc/nou209.15
A PHASE III RANDOMIZED CONTROLLED TRIAL OF SHORT-COURSE RADIOTHERAPY WITH OR WITHOUT CONCOMITANT AND ADJUVANT TEMOZOLOMIDE IN ELDERLY PATIENTS WITH GLIOBLASTOMA (NCIC CTG CE.6, EORTC 26062-22061, TROG 08.02, NCT00482677)
Neuro-Oncology, Volume 16, Issue suppl_3, July 2014, Page iii46, https://doi.org/10.1093/neuonc/nou209.16
