Volume 29, Issue 8, December 2022
Editorials
Response to the multi-country monkeypox outbreak: a view from Africa
COVID-19 vaccines: the imperfect instruments of vaccine diplomacy
Although true vaccine diplomacy in the form of sharing vaccine development technologies and scientific cooperation with low- and middle-income countries has not been a dominant theme in the COVID-19 pandemic, this aspect is now taking off and generating some exciting new possibilities.
Air travel and SARS-CoV-2: many remaining knowledge gaps
COVID-19 is with us indefinitely and air travel is a necessity. Needed research has lagged due to pandemic disruption but must not stall due to COVID indifference. A US government report proposes that national aviation authorities, not health agencies, take the lead. Research priorities and study designs are proposed.
Perspective
Refugee settlements, sewage pollution, COVID-19 and the unfolding cholera outbreak in Lebanon
We have previously documented that the unsanitary conditions in the Syrian refugee settlements and pollution in Lebanon were suitable for the proliferation of infectious diseases. Here, we discuss how cholera is spreading rapidly across Lebanon, where a Syrian man from an informal settlement is thought to be the index case.
Monkeypox and ring vaccination during the FIFA world cup 2022 in Qatar: a call for action
Given the potential spread of monkeypox (MPX) during the FIFA world cup 2022 in Qatar, appropriate precautions should be taken for early containment. Ring vaccination is an appropriate measure in this regard due to its ability not only to break the MPX transmission chain but also to prevent its progression.
Is standby therapy for Covid-19 a practical option for travellers?
International travel has resumed while the risk of SARS-CoV-2 persists, leading to consideration of medications that can treat or prevent Covid-19 when travellers become ill abroad. Nirmatrelvir-ritonavir, molnupiravir and tixagevimab-cilgavimab are available under Emergency Use Authorization or conditional approval. We discuss the potential application of these medications to protect travellers.
Original Articles
Estimating the size of the monkeypox virus outbreak in Nigeria and implications for global control
Seroconversion and antibody persistence after yellow fever vaccination in people living with HIV: impact of baseline HIV viral load and yellow fever seropositivity
Effect of flight connectivity on the introduction and evolution of the COVID-19 outbreak in Canadian provinces and territories
Duration of immune protection of SARS-CoV-2 natural infection against reinfection
Effectiveness of BNT162b2 and CoronaVac vaccinations against SARS-CoV-2 omicron infection in people aged 60 years or above: a case–control study
Shifts in global mobility dictate the synchrony of SARS-CoV-2 epidemic waves
Neutralizing antibodies against SARS-CoV-2 are higher but decline faster in mRNA vaccinees compared to individuals with natural infection
Rapid Communication
Projecting the impact of testing and vaccination on the transmission dynamics of the 2022 monkeypox outbreak in the USA
Serial intervals and incubation periods of the monkeypox virus clades
Estimating serial interval (SI) and incubation period (IP) is necessary to interpret transmission trends and optimize contact tracing and isolation measures. We conducted a systematic review to synthesize the evidence for serial interval and incubation period of the monkeypox virus and further estimated the SI and IP of each clade.
Research Letters
Reproduction number of monkeypox in the early stage of the 2022 multi-country outbreak
Monkeypox, a fast-spreading viral zoonosis outside of Africa in May 2022, has put scientists on alert. We estimated the reproduction number to be 1.39 (95% CrI: 1.37, 1.42) by aggregating all cases in 70 countries as of 22 July 2022.
Global online public interest in monkeypox compared with COVID-19: Google trends in 2022
Resurgence of influenza A infections in children after the relaxation of COVID-19-related social distancing measures and normalization of international travel in Qatar
We report an off-season surge of influenza A infections among children in Qatar coinciding with the relaxation of COVID-19 related social restrictions and the normalization of international travel. The unusual surge may be related to population waning immunity after a prolonged reduced influenza A activity in Qatar.
Reproduction numbers of SARS-CoV-2 Omicron subvariants
Estimating the effective reproduction number of Omicron subvariants is crucial for evaluating the effectiveness of control measures, and adjusting control measures promptly. We conducted a systematic review to synthesize the evidence from estimates of the reproduction numbers for Omicron subvariants, and estimated their effective reproduction number.
Impact of mass rapid antigen testing for SARS-CoV-2 to mitigate Omicron outbreaks in China
We analysed the effectiveness of various non-pharmaceutical interventions in containing the 2022 Omicron outbreak in China. The results show that the Rapid Antigen Test contributed to containing the outbreak, reducing the reproduction number by 0.788 (95% CI:−0.306, 1.880) in studied cities.
Increased imported severe Plasmodium falciparum malaria involving hyperparasitaemia (>10%) in a UK hospital following relaxation of COVID-19 restrictions compared to the pre-pandemic period
We identified and compared patients diagnosed with Plasmodium falciparum malaria at a large hospital in London, UK, prior to the COVID-19 pandemic vs following relaxation of COVID-19-associated restrictions. We found that parasitaemias, rates of hyperparasitaemia and severe malaria were significantly higher in the period post-relaxation of COVID-19 restrictions.