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Childhood 25-OH-vitamin D Levels Predict Early Cardiovascular Outcomes in Adulthood: The Cardiovascular Risk in Young Finns Study
Jussi Niemelä and others
European Journal of Preventive Cardiology, zwaf271, https://doi.org/10.1093/eurjpc/zwaf271
Published: 29 April 2025
... for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. atherosclerosis cardiovascular disease childhood vitamin D levels mortality prevention risk...
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Indications, efficacy, safety of rituximab in childhood-onset systemic lupus erythematosus: a retrospective study of the JIR cohort
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Jade Cognard and others
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Rheumatology
Rheumatology, keaf231, https://doi.org/10.1093/rheumatology/keaf231
Published: 25 April 2025
...-Paut; Linda Rossi-Semerano; Micheline Pha; Michaël Hofer; Samira Plassart; Brigitte Bader-Meunier; Alexandre Belot Rituximab B-cell depletion lupus systemic lupus erythematosus childhood-onset SLE cSLE lupus nephritis treatment safety Rheumatology Page 2 of 28 1 2 3 4 Indications, efficacy...
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Diminished SUV3 expression and its functional implications in the IFN-enriched monocyte subset of childhood Sjögren’s Disease
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Jimin Yoon and others
in
Rheumatology
Rheumatology, keaf193, https://doi.org/10.1093/rheumatology/keaf193
Published: 23 April 2025
... helicase (SUV3) expression in the interferon (IFN)-enriched subset of monocytes from childhood Sjögren’s disease (cSjD). SUV3 is known to unwind double-stranded RNAs (dsRNAs) for homeostatic RNA decay within mitochondria. Methods Using single-cell RNA sequencing, we analysed highly inflammatory IFN...
Journal Article
Screening for psychological problems in deaf and hard of hearing students
Nynke Dethmers and others
The Journal of Deaf Studies and Deaf Education, enaf017, https://doi.org/10.1093/jdsade/enaf017
Published: 21 April 2025
... problems in special schools can be successfully implemented. Such programs will help to identify psychological problems at an early stage and provide care for DHH children and adolescents with psychological problems. deaf hard of hearing emotional and behavioral disorders early childhood adolescence...
Journal Article
Factors influencing parental decisions on food choices during complementary feeding: a qualitative study in Uruguay
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Alejandra Girona and others
Health Promotion International, Volume 40, Issue 2, April 2025, daaf037, https://doi.org/10.1093/heapro/daaf037
Published: 11 April 2025
..., childcare centers, and social norms. These findings underscore the need for comprehensive, multifaceted approaches to improve complementary feeding practices, extending beyond simply enhancing parental knowledge. parental practices socioecological model early childhood complementary feeding ultra...
Journal Article
Welfare benefit cuts in early childhood and future educational outcomes: a natural experiment
Dana Shay and others
Social Forces, soaf042, https://doi.org/10.1093/sf/soaf042
Published: 06 April 2025
... reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work properly cited. For commercial re-use, please contact [email protected] Abstract Understanding the long-term effect of early childhood poverty...
Journal Article
Early childhood education and handgun carrying, serious fighting, and assault charges: a retrospective cohort study
Julia P Schleimer and others
Health Affairs Scholar, Volume 3, Issue 4, April 2025, qxaf070, https://doi.org/10.1093/haschl/qxaf070
Published: 05 April 2025
... was more likely to be in poverty and thus eligible for Head Start (in NLSY97, 75% of Head Start attendees' parent had a high school degree or less). We used parental education as an imperfect proxy for Head Start eligibility because early childhood income/poverty (the main Head Start eligibility criterion...
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Salvage therapies for first relapse of SHH medulloblastoma in early childhood
Craig Erker and others
Neuro-Oncology, noaf092, https://doi.org/10.1093/neuonc/noaf092
Published: 04 April 2025
... reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background Sonic hedgehog (SHH) medulloblastoma is the most common molecular group of infant and early childhood medulloblastoma (iMB) and has no standard of care at relapse. This work aimed...
Journal Article
Diabetes Risk in Young Survivors of Childhood Cancer: A Need for Prevention and Survivor-specific Treatment Strategies
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Stephanie B Dixon
The Journal of Clinical Endocrinology & Metabolism, dgaf202, https://doi.org/10.1210/clinem/dgaf202
Published: 02 April 2025
... ) diabetes mellitus cancer survivors childhood late-effect Children treated for cancer today in North America and across Europe are expected to achieve >80% 5-year survival ( 1 ). This survival comes at the cost of chronic health conditions, including diabetes mellitus, for which survivors experience...
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Lurasidone response in bipolar type I depression with childhood trauma exposure
Hernan F Guillen-Burgos and others
International Journal of Neuropsychopharmacology, pyaf020, https://doi.org/10.1093/ijnp/pyaf020
Published: 29 March 2025
[email protected]. Abstract Importance Childhood Trauma (CT) worse the course of Bipolar Disorder (BD) and negatively impact treatment outcomes. Despite the recognized influence of CT on clinical trajectories, limited evidence exists on how it affects specific pharmacological responses in BD. Objective...
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Co-occurrence of congenital anomalies and childhood brain tumors in 22 million live births
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Thanh T Hoang and others
Neuro-Oncology, noaf087, https://doi.org/10.1093/neuonc/noaf087
Published: 26 March 2025
... childhood or adolescence, but the co-occurrence between specific types of congenital anomalies and specific types of childhood brain tumors (CBTs) is not well described. This study characterized the associations between specific congenital anomalies and CBTs. Methods We leveraged a population-based...
Journal Article
Highlights from the breakout session: vasculitis in paediatric rheumatology
Yagmur Bayindir and others
in
Rheumatology
Rheumatology, Volume 64, Issue Supplement_1, March 2025, Pages i131–i133, https://doi.org/10.1093/rheumatology/keae406
Published: 12 March 2025
... for further refinement of the criteria to improve diagnostic precision. This study is a significant step towards improving the diagnostic criteria for IgA vasculitis in adults and the discussions have paved the way for a slight revision of the criteria. There were more presentations on childhood IgAV. Jelusic...
Journal Article
Adult Growth Hormone Deficiency, Replacement Therapy, and Outcomes in Long-Term Childhood Cancer Survivors
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Tomoko Yoshida and others
The Journal of Clinical Endocrinology & Metabolism, dgaf156, https://doi.org/10.1210/clinem/dgaf156
Published: 08 March 2025
... hormone deficiency (aGHD) among childhood cancer survivors are not well defined. The lack of evidence and socioeconomic factors may contribute to underutilization of growth hormone therapy (GHT) among survivors with aGHD. Objectives This work aimed to examine the association of GHT use...
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The association of childhood HDL cholesterol with atherosclerotic cardiovascular disease events in adults: findings from the International Childhood Cardiovascular Cohort Consortium
Jing Wang and others
European Journal of Preventive Cardiology, zwaf117, https://doi.org/10.1093/eurjpc/zwaf117
Published: 05 March 2025
... Graphical Abstract Childhood HDL-C could be associated with adult ASCVD. There is increasing evidence that ASCVD has its origins in early life. 6 Atherosclerosis, the pathology underlying many ASCVD diagnoses, begins in utero, 7 progresses in mid to late adulthood before...
Journal Article
Genetic Susceptibility to the Environment Moderates the Impact of Childhood Experiences on Psychotic, Depressive, and Anxiety Dimensions
Neus Barrantes-Vidal and others
Schizophrenia Bulletin, Volume 51, Issue Supplement_2, March 2025, Pages S95–S106, https://doi.org/10.1093/schbul/sbad130
Published: 04 March 2025
... del Vallès), Barcelona, Spain; tel: 0034 93 581 38 64, fax: 0034 93 581 21 25, e-mail: [email protected] gene–environment interaction schizotypy psychosis childhood adversity risk factors resilience We applied the classical Clumping + Thresholding (C+T) method with PLINK v1.9. Independent...
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Screening of cytokines-cytokine receptor-associated genes in childhood asthma based on bioinformatics
Caiwen Wang and others
Integrative Biology, Volume 17, 2025, zyaf002, https://doi.org/10.1093/intbio/zyaf002
Published: 27 February 2025
..., gaining an in-depth knowledge of the molecular mechanisms and potential targets causing childhood asthma is of utmost significance. Methods Childhood asthma datasets were obtained from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) between asthmatic child and healthy...
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Parasympathetic Modulation is Correlated With Baroreflex Sensitivity and Orthostatic Pressor Response in Childhood
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Chaima El Khadiri and others
American Journal of Hypertension, hpaf025, https://doi.org/10.1093/ajh/hpaf025
Published: 20 February 2025
... Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract BACKGROUND The objective of our case–control study was to evaluate the determinants of childhood cardio-vagal baroreflex failure and exaggerated orthostatic pressor response, which are risk factors...
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The Moderating Role of Genetic and Environmental Risk Factors for Schizophrenia on the Relationship between Autistic Traits and Psychosis Expression in the General Population
Melike Karacam Dogan and others
Schizophrenia Bulletin Open, Volume 6, Issue 1, January 2025, sgaf005, https://doi.org/10.1093/schizbullopen/sgaf005
Published: 19 February 2025
... risk scores for schizophrenia and psychosis-associated environmental factors (ie, childhood trauma (CT), bullying, negative life events, obstetric complications, cannabis use, winter birth, and hearing impairment) were tested for their independent effects on PEs and their interaction effects with ATs...
Journal Article
An unbreakable bond? Maternal adverse childhood experiences and mothers’ relationships with adult children
Lawrence Stacey and others
Social Forces, soaf022, https://doi.org/10.1093/sf/soaf022
Published: 19 February 2025
.../ ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact [email protected] Abstract Adverse childhood experiences...
Journal Article
Transgenerational inheritance of hepatic steatosis in mice: sperm methylome is largely reprogrammed and inherited but does not globally influence liver transcriptome
Sílvia Ribó and others
Environmental Epigenetics, Volume 11, Issue 1, 2025, dvaf003, https://doi.org/10.1093/eep/dvaf003
Published: 15 February 2025
... spectrum in the next generation offspring. Previously, we established a mouse model of childhood obesity by reducing litter size at birth. Mice raised in small litters (SL) developed obesity, insulin resistance, and hepatic steatosis. The offspring (SL-F1) and grand-offspring (SL-F2) of SL males also...