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Sarah L. Zielinski, Project Creates Repository for Microarray Datasets, JNCI: Journal of the National Cancer Institute, Volume 96, Issue 15, 4 August 2004, Page 1126, https://doi.org/10.1093/jnci/96.15.1126
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As the number of microarray studies increases and more cancer researchers use gene expression technology to search for cancer biomarkers or possible therapeutic targets, those who want to compare datasets face a daunting task: obtaining and compiling all this information from researchers scattered around the world. A new online tool called Oncomine assembles these datasets in one easily searchable site to help researchers take advantage of the vast amount of data available.
Arul Chinnaiyan, M.D., who spearheaded the effort to create the new database, had realized there was a need for a central repository of microarray information when he was asked whether the genes that he found to be differentially expressed in prostate cancer, his field of study, were expressed in other cancer types.
“We wanted to compare data from different platforms and do meta-analyses,” but there were no tools to do this, said Chinnaiyan, associate professor of pathology at the University of Michigan in Ann Arbor. He developed Oncomine “so the average cancer biologist could take advantage of the wealth of information that's out there,” he said.
