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Relating Neuropsychological Test Performance To Cognitive Complaints After Breast Cancer, JNCI: Journal of the National Cancer Institute, Volume 105, Issue 11, 5 June 2013, Page 1, https://doi.org/10.1093/jnci/djt112
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Approximately one out of five breast cancer patients treated for breast cancer had elevated memory and/or executive function complaints that were statistically significantly associated with domain-specific neuropsychological (NP) test performances and depressive symptoms. Combined chemotherapy and radiation treatment in these patients was also associated with memory complaints according to a study published April 18 in the Journal of the National Cancer Institute .
Cognitive complaints have been frequently reported following breast cancer treatments, however, their connection with neuropsychological (NP) test performance has not been well established.
In order to determine the relationship between cognitive complaints and neurocognitive testing, Patricia A. Ganz, M.D., at the Division of Cancer Prevention and Control Research, UCLA Jonsson Comprehensive Cancer Center and colleagues, looked at early-stage post treatment breast cancer patients who were enrolled in a prospective, longitudinal, cohort study before they started receiving endocrine therapy and evaluated them using an NP test battery and questionnaires that were self-reported, which gauged their symptoms, including cognitive complaints.