Volume 50, Issue 5, May 2020

Progress of adjuvant therapy for pancreatic cancer has improved post-resection survival. Recent randomized trials showed the superiority of neoadjuvant therapy versus up-front surgery on survival following planned pancreatic cancer resection.

Brachytherapy is the utmost precision radiation therapy even surpassing the most modern carbon ion therapy in dose distribution.

An overview of all studies conducted by the Japan Clinical Oncology Group Lung Cancer Study Group from 1970s to 2019.

Carbon-11-labeled methionine positron-emission tomography can accurately assess the treatment response of primary central nervous system lymphoma, which is often difficult to assess using magnetic resonance images alone.

For the first time in Japan, health-related quality of life using Expanded Prostate Cancer Index Composite questionnaires in Japanese patients with prostate cancer after proton beam therapy was investigated and compared with other treatment modalities.

This study confirmed the safety of using carbon nanoparticles suspension as a tracer in colorectal cancer, which could significantly increase the detected number of lymph nodes in colorectal cancer.

Sentinel node navigation surgery, not pelvic lymphadenectomy, is the best treatment option for preventing the development of lower extremity lymphedema and pelvic lymphocele in cervical cancer patients.

Different radio-insensitive NPC xenografts underwent radiotherapy. DKI-MRI and tumour histopathological biomarkers were used to evaluate the abilities of them in monitoring the responses of NPC xenografts to radiotherapy.

We carried out a systematic review of primary hepatic angiosarcoma and highlighted the use of routine physical examinations and surgery combined with adjuvant chemotherapy to improve the outcomes.

A systematic review to assess the effectiveness and safety of radiotherapy for desmoid tumors revealed that radiotherapy was valuable in controlling local lesions while the occurrence of developing late toxicities should be considered.

Non-surgical treatment might be appropriate for asymptomatic patients with extra-peritoneal desmoid-type fibromatosis when considering the exacerbation rate and treatment-associated complications.

We used the QCC method to improve the management of cancer pain, and the results showed that cancer pain was well controlled.

The Japanese Psycho-Oncology Society and Japanese Association of Supportive Care in Cancer launched the guidelines for delirium. This article reports the process of developing the guideline and summarizes the recommendations.

The incidence of intracranial metastases for rearranged during transfection-rearranged non-small cell lung cancer was 44%, while the intracranial efficacy of rearranged during transfection inhibitors remains insufficient. Development of a novel tyrosine kinase inhibitor with higher RET selectivity and blood–brain barrier penetration is warranted.

Without related complications, EBUS-TBNA give a sensitivity of 88.9% with an overall diagnostic accuracy of 90.0% and is a safe and effective approach for suspected recurrent intrathoracic masses after esophagectomy.

This study reported outcomes of the treatment with a real-time tumor-tracking radiotherapy system. This therapy is an alternative for patients that are medically unfit for or do not want to undergo cystectomy.

In this retrospective study, a programmed death-ligand 1 (PD-L1) tumor proportion score ≥ 50% was significantly more frequent in non-small cell lung cancer patients harboring uncommon epidermal growth factor receptor (EGFR) mutations and was positively associated with pembrolizumab efficacy.