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Minkyo Song, Hwi-Won Lee, Daehee Kang, The Potential Application of Personalized Preventive Research, Japanese Journal of Clinical Oncology, Volume 44, Issue 11, November 2014, Pages 1017–1024, https://doi.org/10.1093/jjco/hyu135
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Abstract
With increases in life expectancy, the focus has shifted to living a healthier, longer life. By concentrating on preventing diseases before occurrence, researchers aim to diminish the increasing gap in medical costs and health inequalities prevalent across many nations. Although we have entered an era of post-genomics, we are still in infancy in terms of personalized preventive research. Personalized preventive research has and will continue to improve with advancements in the use of biomarkers and risk assessment. More evidence based on well-designed epidemiologic studies is required to provide comprehensive preventive medical care based on genetic and non-genetic profile data. The realization of personalized preventive research requires building of evidence through appropriate methodology, verification of results through translational studies as well as development and application of prediction models.