Extract

Review Articles

Drug Review: Safety and Efficacy of Bevacizumab for Glioblastoma and Other Brain Tumors

Bevacizumab is effective for glioblastoma, and it was recently used to treat radiation necrosis and other brain tumors such as brain metastases, schwannoma and meningioma. The efficacy and problems of bevacizumab therapy are reviewed.

Narita, Y. Jpn J Clin Oncol 2013 43:6 587–595

RNAi Therapeutics and Applications of MicroRNAs in Cancer Treatment

This review provides an overview of RNAi-based therapeutics in clinical trials and describes a wide range of strategies to control the expression levels of endogenous miRNAs.

Uchino, K., Ochiya, T., Takeshita, F. Jpn J Clin Oncol 2013 43:6 596–607

Original Articles

Clinical Trials

Phase II Study of Concurrent Chemoradiotherapy at the Dose of 50.4 Gy with Elective Nodal Irradiation for Stage II–III Esophageal Carcinoma

Chemoradiation therapy at a dose of 50.4 Gy with elective nodal irradiation is promising with a manageable tolerability profile in esophageal squamous cancer patients.

You do not currently have access to this article.