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Fang Fang Li, Alison Faber, Jessica M Caleta, David M Goldfarb, Inna Sekirov, Natalie A Prystajecky, Jocelyn A Srigley, Ram Mishaal, Agatha N Jassem, Clinical Application of Phage Immunoprecipitation Sequencing to Diagnose Enterovirus D68 as the Underlying Etiology in a Case of Guillain-Barré Syndrome, The Journal of Infectious Diseases, Volume 231, Issue 2, 15 February 2025, Pages 490–494, https://doi.org/10.1093/infdis/jiae411
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Abstract
Guillain-Barré syndrome (GBS) is an acute peripheral neuropathy often preceded by respiratory or gastrointestinal infections, though molecular testing of cerebrospinal fluid is often inconclusive. In a recent case of severe pediatric GBS in British Columbia, Canada, we detected cerebrospinal fluid antibodies against enterovirus D to link GBS with prior enterovirus D68 respiratory infection.