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Barbara L. Herwaldt, Anne M. Kjemtrup, Patricia A. Conrad, Robert C. Barnes, Marianna Wilson, Maureen G. McCarthy, Merlyn H. Sayers, Mark L. Eberhard, Transfusion-Transmitted Babesiosis in Washington State: First Reported Case Caused by a WA1-Type Parasite, The Journal of Infectious Diseases, Volume 175, Issue 5, May 1997, Pages 1259–1262, https://doi.org/10.1086/593812
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Abstract
Most cases of babesiosis reported in the United States have been tickborne and caused by Babesia microti, the etiologic agent of all previously described transfusion-transmitted cases. A 76-year-old man with the first recognized case of transfusion-transmitted infection with the recently identified WAl-type Babesia parasite is described. The subject received multiple blood transfusions in 1994. Indirect immunofluorescent antibody testing of serum from 57 blood donors implicated a 34-year-old man (WA1 titer, 1:65,536) whose donation had been used for packed red cells. Isolates of the organisms that infected the recipient and the donor, both of whom were spleen-intact residents of Washington State, were obtained by hamster inoculation. The DNA sequence of a 536-bp region of the nuclear small subunit—rRNA gene of both isolates was identical to that of WA1 (isolated in 1991 from the index WA1 case-patient). Effective measures for preventing transmission of babesiosis by blood transfusion are needed.