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Magnus Evander, Karin Edlund, Åke Gustafsson, Monica Jonsson, Roger Karlsson, Eva Rylander, Goran Wadell, Human Papillomavirus Infection Is Transient in Young Women: A PopulationBased Cohort Study, The Journal of Infectious Diseases, Volume 171, Issue 4, April 1995, Pages 1026–1030, https://doi.org/10.1093/infdis/171.4.1026
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Abstract
The prevalence of human papillomavirus (HPV) infection in cervical cell scrapes from a cohort of 276 young women was determined by a general two-step polymerase chain reaction. HPV infection fluctuated among young women during a 2-year interval. The total prevalence of HPV infection decreased from 21%to 8.3%. The most prevalent HPV types at enrollment were HPV16 (3.3%) and HPV-6 (2.9%). At follow-up, the most common type was HPV-16 (2.9%), while no HPV-6 was detected. In 2 women only, the same HPV type persisted. Regression of HPV infection was found in 80% of the women. A new HPV type-specific infection was detected in 7.2% of the women and was independently associated with a new sex partner or an abnormal smear since enrollment.