-
Views
-
Cite
Cite
Omu A. Anzala, Nico J. D. Nagelkerke, Job J. Bwayo, Donna Holton, Stephen Moses, Elizabeth N. Ngugi, Jackoniah O. Ndinya-Achola, Francis A. Plummer, Rapid Progression To Disease In African Sex Workers With Human Immunodeficiency Virus Type 1 Infection, The Journal of Infectious Diseases, Volume 171, Issue 3, March 1995, Pages 686–689, https://doi.org/10.1093/infdis/171.3.686
- Share Icon Share
Abstract
From a cohort of female sex workers in Nairobi, Kenya, 163 women were observed to seroconvert to human immunodeficiency virus type 1 (HIV-1) and followed to study progression to HIV-I-related disease. The effect of several covariables on disease progression was studied using a Weibull proportional hazards model. The Weibull survival model was fitted to the observed incubation times. Estimates of the median duration to CDC stage IV-A and IV-C disease were 3.5 and 4.4 years, respectively. Condom use before seroconversion was associated with a reduced risk of CDC stage IV-A disease (relative risk = .64, P < .05). The incubation time of HIV-I-related disease is extremely short in this population.