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Michael Heller, Richard D. Dix, J. Richard Baringer, Julius Schachter, John E. Conte, Herpetic Proctitis and Meningitis: Recovery of Two Strains of Herpes Simplex Virus Type 1 from Cerebrospinal Fluid, The Journal of Infectious Diseases, Volume 146, Issue 5, November 1982, Pages 584–588, https://doi.org/10.1093/infdis/146.5.584
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Abstract
A patient with simultaneous proctitis and meningitis due to herpes simplex virus type 1 (HSV-l) and type 2 (HSV-2) was extensively investigated. In both disease locations the infection was clinically evident and culture-proven. Analysis by sodium dodecylsulfatepolyacrylamide gel electrophoresis of rectal isolates revealed both HSV-I and HSV-2. The cerebrospinal fluid harbored two apparently different strains of HSV-1, one of which was shown by restriction endonuclease analysis to be identical with the rectal isolate of HSV-1.