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Gilbert M. Schiff, Gary A. Roselle, Betsy Young, H. Stephen Bjornson, Ann Bjornson, Tom Roue, Don May, Sally Trimble, Evaluation of Influenza A/New Jersey/76 Split-Product Virus Vaccine in a Summer Camp, The Journal of Infectious Diseases, Volume 136, Issue Supplement_3, December 1977, Pages S592–S596, https://doi.org/10.1093/infdis/136.Supplement_3.S592
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Abstract
An evaluation of two doses of split-product A/New Jersey/76 virus vaccines was conducted at a boys' summer camp. Two doses of either 200 chick cell-agglutinating (CCA) or 400 CCA units of vaccine were administered four weeks apart. There were no significant side effects. Of 60 subjects, 59 developed a significant titer of serum antibody after two doses. There was no correlation between titer of antibody and total dose of vaccine. Younger subjects developed a higher titer than older subjects. A single dose of vaccine was insufficient to achieve a protective level of antibody.