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Anne Klibanski, Janet Schlechte, Nicholas Tritos, Diabetes Insipidus, The Journal of Clinical Endocrinology & Metabolism, Volume 98, Issue 7, 1 July 2013, Pages 35A–36A, https://doi.org/10.1210/jcem.98.7.zeg35a
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WHAT IS DIABETES INSIPIDUS (DI)?
Diabetes insipidus, also called DI, is a rare condition that leads to frequent urination (passing a lot of clear urine) and excessive thirst. The condition may be caused by problems with your pituitary gland and/or your kidneys.
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HOW DOES YOUR BODY REGULATE FLUID?
The amount of fluid in your body is a balance between how much liquid you drink and how much urine you make. Your kidneys and bladder are part of the system.
Your kidneys remove extra fluid from your blood. If there's extra fluid in your system, your kidneys send it to your bladder. Your bladder stores and then excretes extra fluid as urine. If you take in less water, the kidneys make less urine and send water back into your blood. ADH is released if you get dehydrated and the sodium level in the blood rises, which helps your kidneys retain water.