Editor's Choice
Background Non-alcoholic fatty liver disease (NAFLD) is common, can progress to cirrhosis and hepatic decompensation, and has no approved medical therapy in Canada. Objective We conducted a systematic review on whether glucagon-like peptide-1 receptor agonists (GLP-1RA) improve non-alcoholic ...
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Endoscopic transpapillary gallbladder drainage (ETGBD) is an alternative to percutaneous transhepatic gallbladder drainage for acute cholecystitis, but its success rate is lower (64%-89%) because of technical difficulty. The direction of the cystic duct contributes to the procedure complexity. 1 ...
Background/Aims Among Crohn’s disease patients with loss of response or non-response to ustekinumab (UST), there remains no clear strategy for dose escalation. Moreover, clinical associations and the role of therapeutic drug monitoring (TDM) are poorly understood. This study assessed response to ...
Background First Nations (FN) people in Canada are commonly diagnosed with colorectal cancers. Although Canada has treaty responsibilities to ensure FNs people have equitable access to quality health services, access to colorectal cancer screening in Canada by FNs people has not been fully ...
Background Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder which can respond to proton-pump inhibitors (PPIs). Genetic variation in the CYP2C19 metabolism gene influences PPI efficacy and adverse effects. Pharmacogenetic testing (PGx) can predict PPI response by analyzing genetic ...
Introduction Patient comfort is an important predictor of patient satisfaction and a quality indicator in endoscopy. The St. Paul’s Endoscopy Comfort Score (SPECS), previously validated for colonoscopy, was assessed for measuring patient comfort during esophagogastroduodenoscopy (EGD). Methods In ...
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