F-151
LONG-TERM OUTCOME OF VIDEO-ASSISTED THORACOSCOPIC SURGERY VERSUS THORACOTOMY FOR PATHOLOGICAL N1 STAGE NON-SMALL CELL LUNG CANCER Free

Objectives: Application of video-assisted thoracoscopic surgery (VATS) was noted in several studies on early stage non-small cell lung cancer. However, it has not been evaluated in advanced stage non-small cell lung cancer. We compared the oncologic outcomes between VATS and open thoracotomy retrospectively, by using propensity score matching.

Methods: We evaluated 276 consecutive patients who underwent lung resection surgery for pathological N1 stage non-small cell lung cancer between January 2000 and December 2011 via a retrospective chart review. We used a propensity score matching analysis for comparing VATS and thoracotomy except clinical T3 and T4 stage patients (based on age, gender, smoking, forced expiratory volume in 1 second [FEV1], diffusing capacity of the lungs for carbon monoxide [DLCO], and clinical T stage).

Results: We performed open thoracotomy in 218 patients and VATS in 58 patients. Patients' demographics were similar between VATS and thoracotomy. However, VATS patients had smaller tumour size than open group (P = 0.012). The difference in the 5-year survival rate and the 5-year disease-free survival rate for the pathological stage were not statistically significant between the VATS and thoracotomy. The propensity matching group is in 156 patients (46 VATS and 110 thoracotomy). Median operative time and median total number of lymph nodes retrieved were similar between the two groups. The propensity matching group is in 156 patients (46 VATS and 110 thoracotomy). Median operative time and median total number of lymph nodes retrieved were similar. However, the hospital stay duration and the chest tube indwelling time were significantly shorter in the VATS group compared to the open group.

Conclusion: VATS for patients with pathological N1 stage non-small cell lung cancer appears to have long-term outcomes of survival and recurrence similar to those with thoracotomy. Therefore, VATS is a feasible approach for patients with pathological N1 stage non-small cell lung cancer.

Disclosure: No significant relationships.