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Deena Abu‐Hassan, Safaa Al‐Hasani, The use of ICSI for all cases of in‐vitro conception, Human Reproduction, Volume 18, Issue 4, April 2003, Pages 893–894, https://doi.org/10.1093/humrep/deg159
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Dear Sir,
We read the article of Oehninger and Gosden (2002) with much interest and would like to congratulate the authors on their eloquent debate. However, we are of the opposite opinion and strongly support the use of ICSI for all indications, and would like to express this opinion in a counter‐argument to that presented by the authors.
The argument is whether or not ICSI should be used for all cases of infertility. On one hand and according to the authors, there is general agreement that ICSI should be used in male factor infertility cases, such as oligoasthenoteratozoospermia, presence of anti‐sperm antibodies, or azoospermia, These cases being diagnosed from an abnormal semen analysis. On the other hand, and strongly disagreed with by Oehninger and Gosden, is the use of ICSI in cases of unexplained infertility (in the presence of normal semen parameters), and in general cases of in‐vitro conception, the argument being that there is a high genetic abnormality risk due to the lack of knowledge as to the reasons of infertility. Other arguments against the use of ICSI include its expense and questions about the safety of the technique and the possibility of the technique inducing damage or genetic abnormalities.
