-
Views
-
Cite
Cite
Andrei L. Brioukhanov, Marie-Claire Durand, Alain Dolla, Corinne Aubert, Response of Desulfovibrio vulgaris Hildenborough to hydrogen peroxide: enzymatic and transcriptional analyses, FEMS Microbiology Letters, Volume 310, Issue 2, September 2010, Pages 175–181, https://doi.org/10.1111/j.1574-6968.2010.02061.x
- Share Icon Share
Abstract
We studied the effect of hydrogen peroxide (H2O2) stress on the anaerobic sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough. In a lactate/sulfate medium, growth was affected from 0.1 mM H2O2 and totally inhibited at 0.7 mM. Surprisingly, transcript analyses revealed that the PerR regulon exhibited opposite regulation in the presence of 0.1 and 0.3 mM H2O2. The variations in peroxidase- and superoxide dismutase-specific activities in the cell-free extracts of H2O2-stressed cultures were related to changes in the corresponding transcript abundance. Our data suggest that sod, sor, ngr and tpx genes, in addition to the PerR regulon, belong to the H2O2 stimulon.