-
Views
-
Cite
Cite
Mattias C.U. Gustafsson, Claes von Wachenfeldt, A novel diffusible substance can overcome the apparent AbrB repression of the Bacillus subtilis fatR promoter, FEMS Microbiology Letters, Volume 199, Issue 2, May 2001, Pages 197–202, https://doi.org/10.1111/j.1574-6968.2001.tb10674.x
- Share Icon Share
Abstract
In this work we present evidence for a novel diffusible extracellular factor that modulates gene expression in Bacillus subtilis. The factor was found when studying the regulation of the fatR-cyp102A3 operon. In a Spo0A− mutant expression of the fatR-cyp102A3 operon was almost abolished. The fatR-cyp102A3 expression defect of a Spo0A− mutant could be overcome either by a mutation in the abrB gene or by a diffusible substance excreted by wild-type, abrB mutant and abrB-spo0A double mutant strains.