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Kazuyuki Ishihara, Tadashi Miura, Yoko Ebihara, Toshiya Hirayama, Shigeru Kamiya, Katsuji Okuda, Shared antigenicity between Helicobacter pylori and periodontopathic Campylobacter rectus strains, FEMS Microbiology Letters, Volume 197, Issue 1, April 2001, Pages 23–27, https://doi.org/10.1111/j.1574-6968.2001.tb10577.x
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Abstract
Periodontopathic Campylobacter rectus strains possess 41- and 68-kDa proteinaceous antigens which share antigenicity with antigens of Helicobacter pylori strains. H. pylori strains have a 54-kDa antigen which reacts with C. rectus strains. We found that the salivary IgA levels against H. pylori were correlated with those against C. rectus. These cross-reactive antigens of C. rectus may affect the serological diagnosis of H. pylori infections, especially when saliva is used. It is possible that these cross-reacting antigens may relate to the induction of immunopathological responses against both microorganisms.