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Sigrid A. Carle, Guixia Hao, Desen Zheng, Tamira Sanni-Sanoussi, Michael J. Talarico, Joshua S. Hilton, Thomas J. Burr, A gene cluster in Agrobacterium vitis homologous to polyketide synthase operons is associated with grape necrosis and hypersensitive response induction on tobacco, FEMS Microbiology Letters, Volume 289, Issue 1, December 2008, Pages 90–96, https://doi.org/10.1111/j.1574-6968.2008.01371.x
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Abstract
Here, we identify a cluster of eight genes on chromosome 2 of Agrobacterium vitis that is associated with the ability of the bacterium to cause a hypersensitive response on tobacco and a necrosis of grape shoot explants. Three of these genes share a high level of structural and sequence similarity to clusters of genes in other bacteria that encode the enzymes for biosynthesis of polyketides and long-chain polyunsaturated fatty acids. No similar gene clusters were discovered in sequenced genomes of other members of Rhizobiales.