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Raymond A Meleady, Ian M Graham, Homocysteine as a Risk Factor for Coronary Artery Disease, Journal of Cardiovascular Risk, Volume 2, Issue 3, 1 June 1995, Pages 216–221, https://doi.org/10.1177/174182679500200306
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Abstract
This article reviews the evidence that homocysteine is a risk factor for coronary artery disease. This evidence ranges from that obtained from in-vitro experiments sometimes using non-physiological concentrations of homocysteine to epidemiological studies involving large numbers of subjects. Despite the variety of studies and methodologies employed, the hypothesis that homocysteine is a risk factor remains plausible. The relationship between certain nutrients and serum homocysteine and the therapeutic implications of this relationship are discussed.
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