Extract

M428

Relationship of self-reported habitual physical activity and brachial artery flow-mediated dilation in healthy adults

M Polovina1, M Ostojic1, V Giga1, T Potpara1, N Mujovic1, M Grujic1

1Institute for Cardiovascular Diseases, Belgrade, Serbia

Topic: Physical activity

Background: Exercise training improves endothelial function in adults with increased cardiovascular risk. The influence of leisure-time physical activity on endothelial function in healthy grown-up individuals is less well established.

Methods: We analysed association of self-reported daily habitual physical activity with brachial artery flow-mediated dilation (FMD) in 115 healthy individuals (age: 21 to 67 yrs, 55 male). Based on self-reported habitual physical activity, participants were divided in 2 subgroups' Subgroup 1 (n=59): ≥30 min of daily brisk walking ± recreational sports (jogging, bicycling, swimming' Î) and Subgroup 2 (n=56): sedentary individuals (<30 min of daily physical activity). Maximal FMD value (FMD%) and FMD time-course (time to the maximal endothelium-dependent dilation) were determined using high-resolution vascular ultrasound, with offline measurements of brachial artery diameter every 10 seconds, 0 to 240 seconds after cuff release.

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