Extract

O385

Randomised comparison of the effects of interval aerobic plus strength training versus interval aerobic training alone on endothelium function in chronic heart failure

ST Dimopoulos1, V Anagnostakou1, E Chatzimichail1, L Karatzanos1, K Malliaras2, N Diakos2, A Tasoulis1, S Nanas1

1Cardiopulmonary Rehabilitation Centre, ‘Evgenidio’ Hospital, University of Athens, Greece, 23rd Clinic of Cardiology, ‘Alexandra’ Hospital, University of Athens, Greece

Topic: Cardiovascular rehabilitation

Purpose: Exercise training confers beneficial effects on endothelial function in patients with chronic heart failure (CHF). However the optimal form of training remains debated. This randomised study compared the effects of interval aerobic combined with strength training versus aerobic training alone on endothelial function in CHF patients.

Methods: We studied 28 consecutive patients in optimally treated, stable CHF who were randomly assigned to 3 times weekly training sessions for 3 months, consisting of a) 40 min of aerobic interval training (30 sec effort − 60 sec rest at intensity ≥ 100% VO2peak) (n=14), versus b) 20 min of similar aerobic, interval training plus 20 min of strength training of various muscle groups (quadriceps, hamstrings, muscles of the shoulder zone, biceps) (n=14). All patients underwent maximal, symptom-limited cardiopulmonary exercise testing and ultrasound evaluation of endothelial function by flow-mediated vasodilation (FMD) before and after the programme.

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