The current situation of subclinical coronary atherosclerosis, CHD, and cholesterol control in women and men with FH.1,10,13 Proposal for equitable and cost-effective LDL-C lowering in FH for both sexes.13–15 ASCVD, atherosclerotic cardiovascular disease; CHD, coronary heart disease; FH, familial hypercholesterolaemia; LDL-C, LDL-cholesterol; PCSK9; proprotein convertase subtilisin/kexin type 9; siRNA, small interfering RNA.
Graphical Abstract

The current situation of subclinical coronary atherosclerosis, CHD, and cholesterol control in women and men with FH.1,10,13 Proposal for equitable and cost-effective LDL-C lowering in FH for both sexes.13–15 ASCVD, atherosclerotic cardiovascular disease; CHD, coronary heart disease; FH, familial hypercholesterolaemia; LDL-C, LDL-cholesterol; PCSK9; proprotein convertase subtilisin/kexin type 9; siRNA, small interfering RNA.

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