A 37-year-old female patient was diagnosed with diffuse large B lymphoma (DLBCL) 10 months ago due to fever and fatigue, and she received standard chemotherapy. This time she was admitted to the hospital due to a space-occupying lesion in the right atrium found by echocardiography. Magnetic resonance imaging revealed that a space-occupying lesion with a size of 22 × 13 mm could be seen in the interventricular groove of the right atrium, which partly protruded into the right atrium, and weak delayed enhancement could be demonstrated in the lesion (Panels A and B). Echocardiography demonstrated a space-occupying lesion located on the right wall of the right atrium with a size of 35 × 19 mm (Panel C). We successfully resected the lesion under cardiopulmonary bypass. The lesion was located on the side wall of the right atrium (Panel D), which is a yellow-brown, hard lump with a size of 23 × 22 mm (Panel E). Pathological examination revealed that coagulation necrosis, stale haemorrhage, fibrous tissue hyperplasia accompanied by inflammatory reaction, and scattered calcification could be seen in the lump (Panels F and G), immunohistochemistry showed that CD45 and CD20 were positive (Panels H and I), which proved that the lump is Pan B-cell phenotype of DLBCL.
Author notes
Honghua Yue and Mei Li contributed equally to this article.
