-
Views
-
Cite
Cite
B Szilveszter, D Oren, M Kolossvary, J Karady, B Vattay, Ά Jermendy, A Bartykowszki, A Panajotu, F Suhai, A Nagy, A Apor, B Merkely, P Maurovich-Horvat, P6050
CT based assessment of left ventricular reverse remodeling after transcatheter aortic valve implantation, European Heart Journal, Volume 39, Issue suppl_1, August 2018, ehy566.P6050, https://doi.org/10.1093/eurheartj/ehy566.P6050 - Share Icon Share
Extract
Background: Severe aortic valve stenosis (AS) results in left sided ventricular (LV) hypertrophy and remodelling. Transcatheter aortic valve implantation (TAVI) has emerged as a safe and effective alternative to surgical aortic valve replacement for patients with severe, symptomatic AS and high surgical risk. Computed tomography angiography (CTA) is progressively being used for the planning and follow-up of TAVI.
Purpose: We aimed to evaluate predictors of left ventricular reverse remodeling after TAVI based on LV mass changes on CT imaging.
Methods: We included a total of eighty patients who underwent retrospectively gated, cardiac CTA for the planning and follow-up of TAVI procedure as part of the RETORIC (Rule out Transcatheter Aortic Valve Thrombosis with post Implantation Computed Tomography) trial. We measured LV mass based on epi- and endocardial contours using a semi-automated software. Presence of hypo-attenuated leaflet thickening (HALT) was evaluated on a consensus read. The Wilcoxon-signed rank test was used to compare pre and post TAVI changes. Uni- and multivariate linear regression models were generated to establish independent factors of LV reverse remodeling.