Extract

Background: In patients with severe aortic valve stenosis (AS) and increased perioperative risk, transcatheter aortic valve implantation (TAVI) is known to be a favourable treatment. Coexistence of pulmonary hypertension (PH) is associated with a poor outcome in general. It is though not known whether this applies for a pure transfemoral cohort.

Purpose: Evaluation whether TF-TAVI is a safe and effective procedure in patients with severe AS and coexisting PH.

Methods: We performed a single center retrospective analysis in 606 patients with severe AS with or without coexisting PH. PH was defined as the middle pulmonary arterial pressure ≥25mmHgmeasured in the pre-interventional right heart catheterisation (RHC). 103 patients with inadequate RHC data and 17 patients with missing 30-day-mortality data were excluded from the study. The remaining 486 patients were divided in two groups based on existence (AS+PH: n=311) or absence (AS-PH: n=175) of PH. 30-day mortality, length of stay, complications and short-term outcome were analyzed according to Valve Academic Research Consortium-2 (VARC II) criteria.

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